356068-12-7

Upstream product

• 74-88-4 methyl iodide 

Downstream Products

• 356068-06-9 (2S,3S,4R,5R,6R)-5-Benzoyloxy-4-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-pent-4-enyloxy-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 356068-08-1 methyl (n-pentenyl 2-O-benzoyl-3-O-benzyl-β-D-glucopyranosid)-uronate 
• 356068-11-6 4-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran-2-carboxylic acid methyl ester 
• 356067-98-6 4-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-3,4-dihydro-2H-pyran-2-carboxylic acid methyl ester 
• 356068-15-0 (2R,3S,4R)-3-Acetoxy-4-benzyloxy-3,4-dihydro-2H-pyran-2-carboxylic acid methyl ester 
• 356067-92-0 (2S,3S,4R)-3-Acetoxy-4-benzyloxy-3,4-dihydro-2H-pyran-2-carboxylic acid methyl ester 
• 356068-09-2 (2R,3S,4R)-4-Benzyloxy-3-hydroxy-3,4-dihydro-2H-pyran-2-carboxylic acid methyl ester 
• 356067-89-5 (2S,3S,4R)-4-Benzyloxy-3-hydroxy-3,4-dihydro-2H-pyran-2-carboxylic acid methyl ester 
• 356067-91-9 (2S,3S,4S,5R,6R)-3,5-Diacetoxy-4-benzyloxy-6-bromo-tetrahydro-pyran-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthetic sulfated glucuronosyl paragloboside (SGPG) and its use for the detection of autoimmune peripheral neuropathies

The sulfated glucuronosyl paragloboside SO4-3-GlcA(β1-3) Gal-(β1-4)GlcNAc(β1-3)Gal-(β1-4)Glcβ(1-1′)Cer (SGPG) is a specific constituent of the peripheral nervous system involved in human dysimmune neuropathies. Although it is highly immunogenic in human pathology, it is not a major constituent of peripheral nerve in humans. Pure SGPG is very difficult to obtain from natural sources, but is needed for the design of efficient and reproducible immunoassays. We describe a new chemical synthesis of this important glycolipid with a stearic tail, including its complete characterization by mass spectrometry and its use in the detection of autoimmune neuropathies.