356522-47-9 Usage
Chemical structure
The compound consists of a piperidine ring with a carboxylic acid group at the 2-position and a sulfonyl group attached to the piperidine nitrogen, with a nitrophenyl group attached to the sulfonyl group.
Pharmaceutical industry use
It is often used as an intermediate in the synthesis of various drugs, particularly in the development of potential anti-inflammatory, analgesic, and anti-cancer agents.
Research laboratory use
Utilized as a building block for the synthesis of new chemical entities for biological studies.
Importance in pharmacology
The presence of the sulfonyl and nitrophenyl groups on the piperidine ring makes 1-[(3-NITROPHENYL)SULFONYL]PIPERIDINE-2-CARBOXYLIC ACID important for its potential pharmacological activity.
Role in drug discovery and development
It serves as a key building block in drug discovery and development due to its unique chemical structure and potential pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 356522-47-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,6,5,2 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 356522-47:
(8*3)+(7*5)+(6*6)+(5*5)+(4*2)+(3*2)+(2*4)+(1*7)=149
149 % 10 = 9
So 356522-47-9 is a valid CAS Registry Number.
356522-47-9Relevant academic research and scientific papers
Pipecolate-sulfonamides for treatment of psychiatric disorders
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, (2013/07/25)
The present invention relates to compounds having a pipecolate sulfonamide scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable
PIPECOLATE-SULFONAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS
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, (2013/07/19)
The present invention relates to compounds having a pipecolate sulfonamide scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable
Pipecolic acid derivatives as small-molecule inhibitors of the legionella MIP protein
Juli, Christina,Sippel, Martin,J?ger, Jens,Thiele, Alexandra,Weiwad, Matthias,Schweimer, Kristian,R?sch, Paul,Steinert, Michael,Sotriffer, Christoph A.,Holzgrabe, Ulrike
, p. 277 - 283 (2011/03/22)
The macrophage infectivity potentiator (MIP) protein is a major virulence factor of Legionella pneumophila, the causative agent of Legionnaires disease. MIP belongs to the FK506-binding proteins (FKBP) and is necessary for optimal intracellular survival a
