356572-08-2

Basic information

• Product Name: 1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride
• Synonyms: 1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride;3. 1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride;7-Hydroxy MeMantine Hydrochloride;1-AMino-3,5-diMethyl-7-hydroxyadaMantane Hydrochloride;3-AMino-5,7-diMethyltricyclo[3.3.1.13,7]decan-1-ol Hydrochloride;MeMantine IMpurity IV (1-AMino-3-Hydroxy-5,7-DiMethyladaMantane);1-Amino-7-hydroxy-3,5-dimethyl Adamantane Discontinued See: H944700;1-Hydroxy-3-Amino-5,7-Dimethyl Adamantine Hcl
• CAS NO: 356572-08-2
• Molecular Formula: C₁₂H₂₁NO*ClH
• Molecular Weight: 231.76
• EINECS: 1312995-182-4
• Product Categories: Amines;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 356572-08-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 304-306°C
• Boiling Point: 305.2 °C at 760 mmHg
• Flash Point: 138.4 °C
• Appearance: /
• Storage Temp.: -20?C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride(356572-08-2)
• EPA Substance Registry System: 1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride(356572-08-2)

Safety Data

• Hazardous Substances Data: 356572-08-2(Hazardous Substances Data)

Usage

Chemical Properties

1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride is White Solid

Uses

Different sources of media describe the Uses of 356572-08-2 differently. You can refer to the following data:
1. 1-Amino-7-hydroxy-3,5-dimethyl Adamantane
2. A metabolite of Memantine (M218000), used for the treatment of neurological disorders.
3. 1-Hydroxy-3-amino-5,7-dimethyladamantane hydrochloride is a metabolite of Memantine (M218000), used for the treatment of neurological disorders.

InChI:InChI=1S/C12H21NO.ClH/c1-9-3-10(2)5-11(13,4-9)8-12(14,6-9)7-10;/h14H,3-8,13H2,1-2H3;1H

Upstream product

• 702-79-4 1,3-dimethyladamantane 
• 707-37-9 1,3-dimethyl-5-adamantanol 
• 63971-25-5 3-amino-5,7-dimethyladamantan-1-ol 
• 351329-87-8 N-(3-hydroxy-5,7-dimethyladamantan-1-yl)acetamide 

Downstream Products

• 356572-15-1 1,1-dibenzylamino-3,5-dimethyl-7-hydroxy-adamantane 
• 356572-22-0 1-(benzyloxycarbonyl)amino-3,5-dimethyl-7-(3-bromopropylcarbonyloxy)adamantine 
• 356572-20-8 1-(benzyloxycarbonyl)amino-3,5-dimethyl-7-hydroxyadamantane 

Relevant articles and documents

Preparation method of memantine hydrochloride impurity C

The invention discloses a preparation method of a memantine hydrochloride impurity C. The preparation method comprises a step of hydrolyzing an intermediate D under an acidic condition to obtain the impurity C. The preparation method has the advantages of novelty, usage of easily available raw materials, simple synthesis and good practicability.

Methods for treating neuropsychiatric disorders with nmda receptor antagonists

The present invention relates to compositions and methods for treating a human patient afflicted with a neuropsychiatric disorder. Specifically, the invention provides for compositions and methods of modulating or antagonizing the activity of neuronal NMD