35674-27-2Relevant academic research and scientific papers
The solid phase synthesis of tri-substituted indoles
Collini, Michael D.,Ellingboe, John W.
, p. 7963 - 7966 (1997)
The palladium-catalyzed solid phase synthesis of tri-substituted indoles is described. The synthesis incorporates three independently variable groups and is ideally suited for the preparation of combinatorial libraries.
A significant enhancement of water vapour uptake at low pressure by amine-functionalization of UiO-67
Ko, Nakeun,Hong, Jisu,Sung, Siyoung,Cordova, Kyle E.,Park, Hye Jeong,Yang, Jin Kuk,Kim, Jaheon
, p. 2047 - 2051 (2015)
The functionalization of UiO-67 with -NH2 groups enhances CO2 and CH4 adsorption at 1 bar and 298 K and positively influences the framework's interaction with water as evidenced by the significant enhancement of water vapo
Thermal decomposition pathways of nitro-functionalized metal-organic frameworks
McDonald, Kyle A.,Ko, Nakeun,Noh, Kyungkyou,Bennion, Jonathan C.,Kim, Jaheon,Matzger, Adam J.
, p. 7808 - 7811 (2017)
The decomposition behavior of high energy metal-organic frameworks (MOFs) with extensive nitration is disclosed. In contrast to the detonation behavior observed in molecular energetic compounds, deflagration transforms cubic MOFs into anisotropic carbon s
Modulating Guest Uptake in Core–Shell MOFs with Visible Light
Mutruc, Dragos,Goulet-Hanssens, Alexis,Fairman, Sam,Wahl, Sebastian,Zimathies, Annett,Knie, Christopher,Hecht, Stefan
supporting information, p. 12862 - 12867 (2019/08/08)
A two-component core–shell UiO-68 type metal–organic framework (MOF) with a nonfunctionalized interior for efficient guest uptake and storage and a thin light-responsive outer shell was prepared by initial solvothermal MOF synthesis followed by solvent-as
Inexpensive NaX (X = I, Br, Cl) as a halogen donor in the practical Ag/Cu-mediated decarboxylative halogenation of aryl carboxylic acids under aerobic conditions
Fu, Zhengjiang,Jiang, Ligao,Zuo, Qianming,Li, Zhaojie,Liu, Yanzhu,Wei, Zhenhong,Cai, Hu
, p. 5416 - 5421 (2018/08/12)
Versatile and practical Ag/Cu-mediated decarboxylative halogenation between readily available aryl carboxylic acids and abundant NaX (X = I, Br, Cl) has been achieved under aerobic conditions in moderate to good yields. The halodecarboxylation is shown to be an effective strategy for S-containing heteroaromatic carboxylic acid and benzoic acids with nitro, chloro and methoxyl substituents at the ortho position. A gram-scale reaction and a three-step procedure to synthesize iniparib have been performed to evaluate the practicality of this protocol. A preliminary mechanistic investigation indicates that Cu plays a vital role and a radical pathway is involved in the transformation.
BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF
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Paragraph 0081; 0082, (2013/09/12)
Provided are a benzamide derivative as shown in formula (I) or a pharmaceutically acceptable salt thereof, and the preparation method and use thereof for preparing a medicine for treating cancer, wherein the group definitions of formula (I) are as set out
Mechanism of retinoid X receptor partial agonistic action of 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5- carboxylic acid and structural development to increase potency
Ohsawa, Fuminori,Yamada, Shoya,Yakushiji, Nobumasa,Shinozaki, Ryosuke,Nakayama, Mariko,Kawata, Kohei,Hagaya, Manabu,Kobayashi, Toshiki,Kohara, Kazutaka,Furusawa, Yuuki,Fujiwara, Chisa,Ohta, Yui,Makishima, Makoto,Naitou, Hirotaka,Tai, Akihiro,Yoshikawa, Yutaka,Yasui, Hiroyuki,Kakuta, Hiroki
, p. 1865 - 1877 (2013/05/09)
We have reported that retinoid X receptor (RXR) partial agonist 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5- carboxylic acid (CBt-PMN, 4a) shows a significant antidiabetes effect in the KK-Ay type 2 diabetes model
Combined study of anion recognition by a carbazole-based neutral tripodal receptor in a competitive environment
Curiel, David,Sanchez, Guzman,Ramirez De Arellano, Carmen,Tarraga, Alberto,Molina, Pedro
experimental part, p. 1896 - 1904 (2012/04/23)
Anion recognition studies have been carried out on a series of neutral synthetic receptors in which carbazole-2-carboxamide has been used as building block. Different ligands which include one to three carbazole units in their structure have been prepared
NOVEL CC-1065 ANALOGS AND THEIR CONJUGATES
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Page/Page column 140, (2010/06/17)
This invention relates to novel analogs of the DNA-alkylating agent CC-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver and/or controllably release one or more of said DNA alkylating agents. The agents, conjugates, and intermediates can be used to treat an illness that is characterized by undesired (cell) proliferation. As an example, the agents and the conjugates of this invention may be used to treat a tumor.
Synthesis of new crosslinkable co-polymers containing a push-pull zinc porphyrin for non-linear optical applications
Monnereau, Cyrille,Blart, Errol,Montembault, Véronique,Fontaine, Laurent,Odobel, Fabrice
, p. 10113 - 10121 (2007/10/03)
In this paper, the synthesis of a crosslinkable co-polymer containing new push-pull arylethynyl zinc porphyrins is described. The synthesis of porphyrin chromophores, analogous to Therien's porphyrin (J. Am. Chem. Soc. 1996, 118, 1497-1503) functionalized
