35675-46-8

Basic information

• Product Name: 3-methyl-4-nitrobenzoyl chloride
• Synonyms: 3-methyl-4-nitrobenzoyl chloride;3-Methyl-4-nitrobenzoic acid chloride;Benzoyl chloride, 3-Methyl-4-nitro-
• CAS NO: 35675-46-8
• Molecular Formula: C₈H₆ClNO₃
• Molecular Weight: 199.59114
• EINECS: 252-670-0
• Mol File: 35675-46-8.mol
• Article Data: 41

Chemical Properties

• Melting Point: 28 °C
• Boiling Point: 299.2°Cat760mmHg
• Flash Point: 134.7°C
• Appearance: /
• Density: 1.386g/cm³
• Vapor Pressure: 0.00121mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: 3-methyl-4-nitrobenzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-4-nitrobenzoyl chloride(35675-46-8)
• EPA Substance Registry System: 3-methyl-4-nitrobenzoyl chloride(35675-46-8)

Safety Data

• Hazardous Substances Data: 35675-46-8(Hazardous Substances Data)

Usage

General Description

3-Methyl-4-nitrobenzoyl chloride is a chemical compound with the molecular formula C8H6ClNO4. This means it is made up of eight carbon atoms, six hydrogen atoms, one nitrogen atom, four oxygen atoms, and one chlorine atom. This substance is also identified by alternate names such as 4-Nitro-3-methylbenzoyl Chloride and 3-Methyl-4-nitrobenzoyl Chloride under the CAS Number 4494-91-4. It falls under the category of an aromatic compound and mainly used in chemical synthesis and pharmaceuticals. While handling this type of chemical, proper protective measures should be taken due to its reactive nature.

InChI:InChI=1/C8H6ClNO3/c1-5-4-6(8(9)11)2-3-7(5)10(12)13/h2-4H,1H3

Upstream product

• 3113-71-1 3-methyl-4-nitrobenzoic acid 

Downstream Products

• 317356-57-3 C₂₉H₂₉BrFN₃O₅ 
• 924309-88-6 tert-butyl (3-methyl-4-nitrophenyl)acetate 
• 316121-73-0 tert-butyl 4-amino-3-methylphenylacetate 
• 316121-74-1 (4-[N'-(2-methylphenyl)ureido]-3-methylphenyl)acetic acid 
• 316121-86-5 (4-[N'-(2-chlorophenyl)ureido]-3-methylphenyl)acetic acid 
• 316121-87-6 (4-[N'-(2-bromophenyl)ureido]-3-methylphenyl)acetic acid 
• 317356-54-0 tert-butyl 4-[N'-(2-chlorophenyl) ureido]-3-methylphenylacetate 
• 317356-56-2 tert-butyl 4-[N'-(2bromophenyl) ureido]-3-methylphenylacetate 
• 317356-53-9 C₃₀H₃₂FN₃O₅ 
• 317356-55-1 methyl 4-[(2S,4S)-1-[4-[N'-(2-chlorophenyl)ureido]-3-methylphenylacetyl]-4-fluoro-2-pyrrolidinyl]methoxybenzoate 
• 124895-00-7 4-amino-3-methylhippuric acid 
• 112740-76-8 4-amino-N-[2-(dimethylamino)ethyl]-3-methylbenzamide 
• 99584-85-7 3-methyl-4-nitro benzamide 
• 383666-73-7 ethyl 3-(3-methyl-4-nitrophenyl)-3-oxopropionate 

Relevant articles and documents

Compound based on benzimidazole substituted phenyl n-butylamide and preparation method of compound

The invention relates to a compound based on benzimidazole substituted phenyl n-butylamide and a preparation method of the compound. According to the method disclosed by the invention, nitrification and polyphosphoric acid cyclization reactions are avoided, and the generation of a large amount of waste acid reaction liquid is avoided from the source. The synthesis method disclosed by the inventionhas the advantages of simplicity, high efficiency, mild conditions, less pollutants and the like, and is suitable for being developed into a green sustainable production process.

Spiro-bis-benzoxazole diamine and preparation method and application thereof, polyimide and preparation method and application thereof

The invention belongs to the technical field of macromolecules, and particularly relates to spirobibenzoxazole diamine, a preparation method and application thereof, polyimide and a preparation method and application thereof. According to the present invention, the spiro-bis-benzoxazole diamine is adopted as the monomer to prepare the polyimide, and the spiro structure is introduced into the diamine structure, such that the obtained polyimide has excellent solubility and excellent processability; meanwhile, the polyimide forms a microporous structure, so that the gas permeability of the polyimide is improved.

Novel commercial scale synthetic approach for 5-cyanoindole: A potential intermediate for vilazodone hydrochloride, an antidepressant drug

Present work describes the synthesis of 5-cyanoindole, a common intermediate used in various synthetic route of the antidepressant vilazodone hydrochloride. The protocol is both robust and commercially viable, utilizing readily available and low-cost materials and the isomers are environmental friendly than previously reported routes through its evading use of cyanide reagents and heavy metals.