35688-09-6

Basic information

• Product Name: 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione
• Synonyms: 1,6-Dihydroxy-3-(hydroxymethyl)-8-methoxy-9,10-anthracenedione; 1,6-Dihydroxy-3-(hydroxymethyl)-8-methoxy-9,10-anthraquinone; 9,10-anthracenedione, 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxy-
• CAS NO: 35688-09-6
• Molecular Formula: C₁₆H₁₂O₆
• Molecular Weight: 300.2629
• Mol File: 35688-09-6.mol

Chemical Properties

• Boiling Point: 630.5°C at 760 mmHg
• Flash Point: 241.4°C
• Density: 1.549g/cm³
• Vapor Pressure: 9.12E-17mmHg at 25°C
• Refractive Index: 1.708
• CAS DataBase Reference: 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione(35688-09-6)
• EPA Substance Registry System: 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione(35688-09-6)

Safety Data

• Hazardous Substances Data: 35688-09-6(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione is used as a building block in organic synthesis for the creation of novel compounds with potential applications in various fields due to its reactive functional groups and unique structural features.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione is used as a precursor or intermediate in the development of pharmaceuticals, leveraging its ability to interact with biological targets for therapeutic purposes.
Used in Dye Chemistry:
1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione is utilized as a dyestuff in dye chemistry, capitalizing on its structural attributes to produce colorants for various applications, including textiles, inks, and pigments.
Used in Material Science:
In material science, 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione is employed in the development of new materials, potentially contributing to the creation of advanced materials with specific properties, such as optical, electronic, or mechanical characteristics.
Used in Research on Natural Products and Analogs:
1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione is used as a subject of study in research focused on the synthesis and properties of natural products and their analogs, providing insights into the structure-activity relationships and potential applications of similar compounds.

Upstream product

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Relevant articles and documents

Characterization of emodin metabolites in Raji cells by LC-APCI-MS/MS

A rapid, simple, and sensitive liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry (LC-APCI-MS/MS) method was developed for the identification and quantification of emodin metabolites in Raji cells, using aloe-emodin as an internal standard. Analyses were performed on an LC system employing a Cosmosil 5C18 AR-II column and a stepwise gradient elution with methanol-20 mM ammonium formate at a flow rate of 1.0 mL/min operating in the negative ion mode. As a result, the starting material emodin and its five metabolites were detected by analyzing extracts of Raji cells that had been cultivated in the presence of emodin. The identification of the metabolites and elucidation of their structures were performed by comparing their retention times and spectral patterns with those of synthetic samples. In addition to the major metabolite 8-O-methylemodin, four other metabolites were assigned as ω-hydroxyemodin, 3-O-methyl-ω-hydroxyemodin, 3-O-methylemodin (physcion), and chrysophanol.