357-85-7

Upstream product

• 82086-95-1 1,1,2r,3t,4,4,5t,6c-octafluoro-cyclohexane 
• 2367-82-0 1,2,3,5-tetrafluorobenzene 
• 65337-53-3 1,1,2r,3c,4,4,5t,6t-octafluoro-cyclohexane 
• 1526-36-9 (+/-)-1,1,2r,3c,4,4,5c,6t-octafluoro-cyclohexane 
• 1526-36-9 (+/-)-1,1,2r,3t,4,4,5c,6t-octafluoro-cyclohexane 
• 71-43-2 benzene 

Downstream Products

• 2367-82-0 1,2,3,5-tetrafluorobenzene 
• 1514-85-8 2,2-difluoromalonic acid 
• 363-72-4 Pentafluorobenzene 

Relevant academic research and scientific papers

Fluorination of tetrafluorobenzenes C6HF4R with XeF2

Replacement of hydrogen by fluorine and addition of fluorine atoms to the aromatic ring were found in the reaction of XeF2 with 1-R-2,3,4,5-tetrafluorobenzene (R = H, F, Br, NO2) or 1-R-2,3,4,6-tetrafluorobenzene (R = H, CF3) in HF or CH2Cl2-BF3·OEt2. Only fluorine addition took place in the case of 1-R-2,3,5,6-tetrafluorobenzenes (R = H, Br, CF3) or 1-Br-2,3,4,6-tetrafluorobenzene. The role of cation radicals as reactive intermediates is discusseed.