35700-12-0

Upstream product

• 114647-58-4 (1α,2β-3α)-2-nitromethyl-3-<(tetrahydro-2H-pyran-2-yl)oxy>-5-oxo-cyclopentane acetic acid methyl ester 
• 53813-10-8 (3aα,4α,5β,6aα)-hexahydro-4-nitromethyl-5-<(tetrahydro-2H-pyran-2-yl)oxy>-2H-cyclopentafuran-2-one 
• 88147-22-2 3-<(tetrahydro-2H-pyran-2-yl)oxy>-5-oxo-1-cyclopentene-1-acetic acid methyl ester 
• 114647-63-1 (3aS,4R,5S,6aR)-4-(5-Pentyl-isoxazol-3-yl)-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-one 
• 114647-64-2 (3aS,4R,5S,6aR)-4-(5-Pentyl-isoxazol-3-yl)-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-ol 
• 88147-21-1 2-methoxycarbonylmethyl-4-hydroxy-2-cyclopenten-1-one 
• 57026-61-6 5-oxo-1-cyclopenten-1-acetic acid methyl ester 
• 114647-65-3 (1α,2β,3α,5α)-7<2-(5-pentyl-3-isoxazolyl)-3-(tetrahydro-2H-pyran-2-yl)-oxy-5-hydroxy cyclopentyl>-hept-5(Z)enoic acid 

Relevant academic research and scientific papers

STEREOSPECIFIC NITROMETHANE CONJUGATE ADDITION TO 4-OXYGENATED-2-SUBSTITUTED-CYCLOPENT-2-ENONES: A SIMPLE APPROACH TO PROSTAGLANDINS

The compatibility of nitromethane conjugate addition to 2-cyclopentenones bearing a 4-oxygenated function has been illustrated through a short and practical synthesis of the Corey aldehyde, a key intermediate in prostaglandin synthesis, in both racemic and optically active form.A new synthesis of PGF2α featuring the introduction of the ω-chain via cycloaddition has been also described.