35710-86-2Relevant academic research and scientific papers
Carbon dioxide induced phase switching for homogeneous-catalyst recycling
Desset, Simon L.,Cole-Hamilton, David J.
supporting information; experimental part, p. 1472 - 1474 (2009/07/25)
SwitchPhos: Rhodium complexes formed from PPh3 ligands functionalized with weakly basic amidine groups are highly active catalysts for the hydroformylation of alkenes. On bubbling with CO2 in the presence of water, the yellow rhodium complexes move into the water phase, whereas bubbling with N2 at 60 °C causes them to switch back into the organic phase. The catalysts can be used for reactions in water or an organic phase.
Palladium catalysed coupling reactions using guanidinium phosphine complexes on glass beads
Leese, Mathew P.,Williams, Jonathan M. J.
, p. 1645 - 1647 (2007/10/03)
Supported palladium catalysts generated from guanidinium phosphine 1 and palladium acetate have been shown to exhibit high activity and low leaching of catalyst. The nature of the catalyst allows facile separation and recycling.
Water Soluble Cationic Phosphine Ligands Containing m-Guanidinium Phenyl Moieties. Syntheses and Applications in Aqueous Heck Type Reactions
Hessler, Antonella,Stelzer, Othmar,Dibowski, Harald,Worm, Karin,Schmidtchen, Franz P.
, p. 2362 - 2369 (2007/10/03)
Cationic phosphine ligands containing m-guanidinium phenyl substituents {Ph3-nP[C6H4-m-NHC(NH2)(NMe 2)]n}n+ nCl- (n = 1-3) (17a-c) have been obtained by addition of dimethylcyanamide to the amino groups of tertiary (m-aminophenyl)phosphines in acidic medium. The tertiary (m-aminophenyl)phosphines Ph3-nP(C6H4-m-NH2)n (4a-c) were prepared by reaction of (3-[N,N-bis(trimethylsilyl)amino]phenyl)magnesium chloride (1) with chlorophosphines Ph3-nPCln followed by deprotection of the bis(trimethylsilyl)amino groups with methanol. Using a similar protected group synthesis as above, the secondary (m-aminophenyl)phosphine Ph(H)PC6H4-m-NH2 (7) could be prepared as well. It may be employed as a building block for the syntheses of chiral bidentate phosphine ligands (11, 14, and 15) bearing m-aminophenyl substituents. The guanidinium phosphines 17b and 17c are readily soluble in water. A comparative study of 17b and 17c, the aryl alkyl guanidinium phosphines 18 and 19, and TPPTS (P(C6H4-m-SO3Na)3) in the aqueous phase palladium-catalyzed C-C coupling reaction between p-iodobenzoate and (trifluoroacetyl)propar-gylamine shows 17b to be of surmounting activity.
