35711-47-8

Basic information

• Product Name: 2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE
• Synonyms: UKRORGSYN-BB BBV-074075;2,5-dimethyl-1-pyridin-3-yl-1H-pyrrole-3-carbaldehyde(SALTDATA: FREE);2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrole-3-carbaldehyde;2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE;AKOS BB-2991;CHEMBRDG-BB 6876726;ASISCHEM S96547;TIMTEC-BB SBB010991
• CAS NO: 35711-47-8
• Molecular Formula: C12H12N2O
• Molecular Weight: 200.24
• Mol File: 35711-47-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 367.7°C at 760 mmHg
• Flash Point: 176.2°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 1.34E-05mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE(35711-47-8)
• EPA Substance Registry System: 2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE(35711-47-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 35711-47-8(Hazardous Substances Data)

Usage

General Description

2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE is a chemical compound with the molecular formula C15H14N2O. It is a heterocyclic aromatic compound that contains a pyrrole ring and a pyridine ring, as well as a carbonyl group. 2,5-DIMETHYL-1-PYRIDIN-3-YL-1H-PYRROLE-3-CARBALDEHYDE is commonly used in organic synthesis and pharmaceutical research due to its unique structure and potential biological activities. It has been studied for its potential therapeutic applications in various diseases, including cancer and inflammatory disorders. Furthermore, it is known to have antioxidant and antimicrobial properties, making it a versatile compound in the field of medicinal chemistry.

InChI:InChI=1/C12H12N2O/c1-9-6-11(8-15)10(2)14(9)12-4-3-5-13-7-12/h3-8H,1-2H3

Upstream product

• 110-13-4 2,5-hexanedione 
• 91349-99-4 3-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 462-08-8 pyridin-3-ylamine 

Relevant articles and documents

ANDROGEN RECEPTOR ANTAGONISTS

Compounds that inhibit the androgen receptor, pharmaceutical compositions comprising one or more of the compounds, as well as methods of treating cancer using such compounds are described.

Discovery and structure-activity relationships of pyrrolone antimalarials

In the pursuit of new antimalarial leads, a phenotypic screening of various commercially sourced compound libraries was undertaken by the World Health Organisation Programme for Research and Training in Tropical Diseases (WHO-TDR). We report here the detailed characterization of one of the hits from this process, TDR32750 (8a), which showed potent activity against Plasmodium falciparum K1 (EC50 ～ 9 nM), good selectivity (>2000-fold) compared to a mammalian cell line (L6), and significant activity against a rodent model of malaria when administered intraperitoneally. Structure-activity relationship studies have indicated ways in which the molecule could be optimized. This compound represents an exciting start point for a drug discovery program for the development of a novel antimalarial.