35717-22-7

Upstream product

• 132981-59-0 2,5-dichloro-3-phenylthiophene 
• 2404-87-7 3-phenylthiophene 
• 35717-21-6 2-chloro-4-phenylthiophene 

Downstream Products

• 2404-87-7 3-phenylthiophene 
• 134640-58-7 5-chloro-4,4'-diphenyl-2,2'-bithiophene 
• 108983-34-2 2-(p-methoxyphenyl)-4-phenylthiophene 
• 134640-51-0 4,4'-diphenyl-2,2'-bithiophene 

Relevant academic research and scientific papers

Synthesis of unsymmetrical 2,3-diaryl- and 2,4-diarylthiophenes starting from 2,5-dichlorothiophene

Unsymmetrically substituted 2,4-diaryl- and 2,3-diarylthiophenes were synthesized from 2,5-dichlorothiophene via 4-aryl-2-chlorothiophenes in two and four steps including Ni-mediated cross-coupling, respectively. Aluminum chloride-catalyzed reaction of 3-aryl-2-chlorothiophenes with some aromatic ethers unexpectedly led to the formation of the corresponding 2,4-isomers.

Synthesis of 3,4'-Diaryl- and 4,4'-Diaryl-2,2'-bithienyls from 2,5-Dichlorothiophene

3,4'-Diaryl- and 4,4'-diaryl-2,2'-bithienyls, new classes of mixed thiophene-arene oligomers, were synthesized from 2,5-dichlorothiophene via 4-aryl-2-chlorothiophene in three and two steps, respectively.Namely, a Friedel-Crafts type self-condensation of 4-aryl-2-chlorothiophene, followed by catalytic dechlorination, yielded unsymmetrical bithienyls.Homocoupling of 4-aryl-2-chlorothiophene using a nickel-phosphine catalyst gave symmetrical bithienyls.