357172-87-3

Upstream product

• 643-79-8 o-phthalic dicarboxaldehyde 
• 216572-79-1 (E)-3-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-acrylic acid methyl ester 
• 216572-78-0 3-(2-hydroxymethylphenyl)acrylic acid methyl ester 
• 52753-91-0 (E)-methyl 3-(2-formylphenyl)acrylate 

Downstream Products

• 357172-88-4 Methoxy-acetic acid 10-[1-[2-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-cyclodeca-2,8-diynyl ester 
• 357172-82-8 Acetic acid 10-[1-[2-(tert-butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-cyclodeca-2,8-diynyl ester 
• 357172-80-6 2-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-10-iodo-deca-3,9-diynal 
• 357172-81-7 10-[1-[2-(tert-Butyl-dimethyl-silanyloxymethyl)-phenyl]-meth-(E)-ylidene]-cyclodeca-2,8-diynol 
• 357172-89-5 Methoxy-acetic acid 10-[1-(2-hydroxymethyl-phenyl)-meth-(E)-ylidene]-cyclodeca-2,8-diynyl ester 
• 357172-85-1 Acetic acid 10-[1-(2-hydroxymethyl-phenyl)-meth-(E)-ylidene]-cyclodeca-2,8-diynyl ester 

Relevant academic research and scientific papers

Neighboring nucleophilic group assisted rearrangement of allylic esters under Eu(fod)3 catalysis

The acetate 13a and methoxyacetate 13b of (E)-3-hydroxy-4-(arylmethylidene)cyclodeca-1,5-diyne possessing a free hydroxy group underwent an allylic rearrangement at 20°C in the presence of catalytic Eu(fod)3 to give the enediyne 14 in excellent yields. In contrast, the acetate 10a with a silyloxy group failed to rearrange under the same conditions. These results demonstrated that an internal nucleophilic group promotes the Eu(fod)3-catalyzed rearrangement of allylic esters under mild conditions.