357205-18-6

Upstream product

• 32462-30-9 (S)-hydroxyphenylglycine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 225517-15-7 (S)-N^α-(tert-butyloxycarbonyl)-4-hydroxyphenylglycine methyl ester 

Downstream Products

• 906552-96-3 [1-(4-{4'-[4-(1-tert-butoxycarbonylamino-2-hydroxy-ethyl)-phenoxy]-1,1'-dioxy-[2,2']bipyridinyl-4-yloxy}-phenyl)-2-hydroxy-ethyl]-carbamic acid tert-butyl ester 
• 1391355-45-5 (S)-4-hydroxyphenylglycinol hydrochloride 

Relevant academic research and scientific papers

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Chiral borromeates

The fellowship of the rings: Circular dichroism measurements reveal that chirality is transferred from 12 stereogenic centers to 6 octahedral zinc(II) centers (see picture) in two enantiomeric pairs of chiral Borromeates, one of which has been found to be

The anandamide membrane transporter. Structurea€"activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region

A new series of arachidonic and oleic acids derivatives, most of which with aromatic moieties in the head group region, has been synthesized and evaluated as inhibitors of anandamide uptake. A new series of anandamide and N-oleoylethanolamine analogs, most of which with aromatic moieties in the head group region, has been synthesized and evaluated as inhibitors of anandamide uptake. Some of them efficaciously inhibit the uptake process with Ki values in the low micromolar range (2.4-21.2 μM). Strict structural requisites are needed to observe a significant inhibition and in no case inhibition of fatty acid amidohydrolase overlaps with inhibition of anandamide uptake.