357263-51-5Relevant academic research and scientific papers
Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
-
Page 81, (2008/06/13)
This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.
Antiviral azaindole derivatives
-
, (2008/06/13)
The present invention is directed to a series of chemical entities that express HIV-1 inhibitory activities.
Antiviral azaindole derivatives
-
, (2008/06/13)
The present invention is directed to a series of chemical entities that express HIV-1 inhibitory activities.
An effective procedure for the acylation of azaindoles at C-3
Zhang, Zhongxing,Yang, Zhong,Wong, Henry,Zhu, Juliang,Meanwell, Nicholas A.,Kadow, John F.,Wang, Tao
, p. 6226 - 6227 (2007/10/03)
Conditions for attachment of acetyl chloride, benzoyl chloride, and chloromethyl oxalate to the 3-position of 4-, 5-, 6-, or 7-azaindoles were explored. Best results were achieved with an excess of AlCl3 in CH2Cl2 followed
