35728-02-0 Usage
Uses
Used in Agricultural Industry:
2,4-Dichloro-6-[[3-(trifluoromethyl)phenyl]amino]-1,3,5-benzenetricarbonitrile is used as a herbicide for controlling a wide range of broadleaf weeds in various crops, turf, pastures, and non-crop lands. It is effective in disrupting the growth and development of targeted plants, leading to their death and ensuring the healthy growth of desired vegetation.
Used in Pharmaceutical Research:
2,4-Dichloro-6-[[3-(trifluoromethyl)phenyl]amino]-1,3,5-benzenetricarbonitrile is also used in pharmaceutical research as a potential agent for the treatment of cancer and other diseases. Its ability to inhibit certain cellular pathways makes it a candidate for further investigation into its therapeutic potential. However, more studies are needed to fully understand its mechanism of action and safety profile for human use.
Check Digit Verification of cas no
The CAS Registry Mumber 35728-02-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,2 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 35728-02:
(7*3)+(6*5)+(5*7)+(4*2)+(3*8)+(2*0)+(1*2)=120
120 % 10 = 0
So 35728-02-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H5Cl2F3N4/c17-13-10(5-22)14(18)12(7-24)15(11(13)6-23)25-9-3-1-2-8(4-9)16(19,20)21/h1-4,25H
35728-02-0Relevant academic research and scientific papers
Synthesis and antiinflammatory evaluation of substituted isophthalonitriles, trimesonitriles, benzonitriles, and terephthalonitriles
Heilman,Battershell,Pyne,Goble,Magee
, p. 906 - 913 (2007/10/06)
In an effort to develop nonacidic, nonsteroidal, antiinflammatory agents without gastrointestinal complications, a series of cyanobenzenes was synthesized for antiinflammatory evaluation. Twenty-seven substituted isophthalonitriles, 19 trimesonitriles, 30 benzonitriles, and 16 terephthalonitriles were tested in the rat utilizing the carrageenan-induced pedal edema assay. Based on the performance of phenylbutazone in this assay (43.8% reduction at 100 mg/kg), six compounds, dosed at 50 mg/kg, produced reductions in inflammation comparable to this standard. However, the LD50 value of each compound dosed at this level was in the range of 40-56 mg/kg in the mouse; therefore, further study was not warranted. Fifteen compounds possessed activity in excess of 20% reduction at 200 mg/kg and also possessed LD50 values greater than 300 mg/kg. Of these cyanobenzenes, trimesonitrile, 4-chlorobenzonitrile, 2-chloroterephthalonitrile, and 2-fluoroterephthalonitrile with reductions in edema of 32, 30, 46, and 49%, respectively, represent the best candidates for subsequent study.
