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Tetrahydrothiamine pyrophosphate (TPP) is a coenzyme derived from thiamine (vitamin B1) that plays a crucial role in cellular energy production. It is involved in the metabolism of carbohydrates and branched-chain amino acids, serving as a cofactor for several enzymes in the citric acid cycle, which is the central pathway for energy production in cells. TPP facilitates the transfer of acetyl groups and helps produce ATP, the primary energy currency of the cell. Its role in energy metabolism makes TPP essential for maintaining proper functioning of the nervous system, muscles, and other tissues. Deficiency in TPP or thiamine can lead to a range of health problems, including neurological disorders and metabolic dysfunction.

35728-83-7

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35728-83-7 Usage

Uses

Used in Pharmaceutical Industry:
Tetrahydrothiamine pyrophosphate is used as a therapeutic agent for treating thiamine deficiency and its associated health problems, such as beriberi, Wernicke-Korsakoff syndrome, and other neurological disorders. It helps in maintaining proper functioning of the nervous system, muscles, and other tissues.
Used in Nutritional Supplements:
Tetrahydrothiamine pyrophosphate is used as a dietary supplement to support energy production and overall health. It can be found in multivitamins and B-complex vitamins, ensuring adequate intake of thiamine for optimal cellular metabolism and preventing deficiency-related issues.
Used in Food and Beverage Industry:
Tetrahydrothiamine pyrophosphate is used as a food additive to fortify products with thiamine, ensuring that consumers meet their daily requirements for this essential nutrient. It can be added to various food items, such as cereals, bread, and beverages, to improve their nutritional value and support energy metabolism in the body.

Check Digit Verification of cas no

The CAS Registry Mumber 35728-83-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,2 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 35728-83:
(7*3)+(6*5)+(5*7)+(4*2)+(3*8)+(2*8)+(1*3)=137
137 % 10 = 7
So 35728-83-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H22N4O7P2S/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,8,11H,3-4,6-7H2,1-2H3,(H,20,21)(H2,13,14,15)(H2,17,18,19)

35728-83-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazolidin-5-yl]ethyl phosphono hydrogen phosphate

1.2 Other means of identification

Product number -
Other names Tetrahydrothiamin pyrophosphate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35728-83-7 SDS

35728-83-7Upstream product

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