35732-94-6

Basic information

• Product Name: [R-(Z)]-12-hydroxy-9-octadecenamide
• Synonyms: [R-(Z)]-12-hydroxy-9-octadecenamide;RICINOLEAMIDE;(9Z,12R)-12-Hydroxy-9-octadecenamide
• CAS NO: 35732-94-6
• Molecular Formula: C₁₈H₃₅NO₂
• Molecular Weight: 297.476
• EINECS: 252-703-9
• Mol File: 35732-94-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 476.7°Cat760mmHg
• Flash Point: 242.1°C
• Appearance: /
• Density: 0.935g/cm³
• Vapor Pressure: 4.32E-11mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: [R-(Z)]-12-hydroxy-9-octadecenamide(CAS DataBase Reference)
• NIST Chemistry Reference: [R-(Z)]-12-hydroxy-9-octadecenamide(35732-94-6)
• EPA Substance Registry System: [R-(Z)]-12-hydroxy-9-octadecenamide(35732-94-6)

Safety Data

• Hazardous Substances Data: 35732-94-6(Hazardous Substances Data)

Usage

General Description

[R-(Z)]-12-hydroxy-9-octadecenamide, also known as erucamide, is a fatty acid primary amide. It is commonly used as a slip agent in the production of various polymers such as polyethylene, to improve the surface properties and reduce friction. Erucamide is also used as a lubricant in various industrial applications, as well as a processing aid in the production of plastic films and packaging materials. Additionally, it has been found to have potential therapeutic effects, such as anti-inflammatory and anti-cancer properties, making it a subject of interest for research in the pharmaceutical industry. [R-(Z)]-12-hydroxy-9-octadecenamide is generally considered safe for use in food packaging and other consumer products.

InChI:InChI=1/C18H35NO2/c1-2-3-4-11-14-17(20)15-12-9-7-5-6-8-10-13-16-18(19)21/h9,12,17,20H,2-8,10-11,13-16H2,1H3,(H2,19,21)/b12-9+

Upstream product

• 141-24-2 methyl ricinoleate 

Relevant articles and documents

Antimicrobial Potential of Chiral Amide Derivatives of Ricinoleic and 3-Hydroxynonanoic Acid

The growing role of fatty acid amides in medicinal chemistry has recently been observed. Therefore, using simple and fast methods, a series of chiral amide derivatives (24 compounds) of ricinoleic and 3-hydroxynonanoic acid was obtained with 31–95% yields. Then, the evaluation of their antimicrobial activity against 13 microorganisms representing Gram-positive and Gram-negative bacteria, yeast, and molds was performed. The obtained compounds showed antimold potential; however, the tested species of molds were more susceptible to derivatives of 3-hydroxynonanoic acid than to amides obtained from ricinoleic acid (RA). Interestingly, hydroxamic acids derived from RA exhibited the best activity against Candida albicans and Candida tropicalis. On the other hand, hydroxamic acids derived from 3-hydroxynonanoic acid showed the best antimicrobial potential against the remaining tested microorganisms, especially against Pseudomonas cedrina. The obtained derivatives can be considered compounds of potential pharmacological significance, which is important due to the increasing problem of microbial resistance.