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35737-10-1

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35737-10-1 Usage

Chemical Properties

white to light yellow crystal powde

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs.

Check Digit Verification of cas no

The CAS Registry Mumber 35737-10-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,3 and 7 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 35737-10:
(7*3)+(6*5)+(5*7)+(4*3)+(3*7)+(2*1)+(1*0)=121
121 % 10 = 1
So 35737-10-1 is a valid CAS Registry Number.
InChI:InChI=1/C18H17NO4/c20-17(21)9-10-19-18(22)23-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,19,22)(H,20,21)/p-1

35737-10-1 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (H59887)  N-Fmoc-beta-alanine, 99%   

  • 35737-10-1

  • 5g

  • 323.0CNY

  • Detail
  • Alfa Aesar

  • (H59887)  N-Fmoc-beta-alanine, 99%   

  • 35737-10-1

  • 25g

  • 1613.0CNY

  • Detail
  • Aldrich

  • (47587)  Fmoc-β-Ala-OH  ≥99.0% (HPLC)

  • 35737-10-1

  • 47587-5G-F

  • 307.71CNY

  • Detail
  • Aldrich

  • (47587)  Fmoc-β-Ala-OH  ≥99.0% (HPLC)

  • 35737-10-1

  • 47587-25G-F

  • 1,454.31CNY

  • Detail

35737-10-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

1.2 Other means of identification

Product number -
Other names N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-β-alanine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35737-10-1 SDS

35737-10-1Relevant articles and documents

Unwanted hydrolysis or α/β-peptide bond formation: How long should the rate-limiting coupling step take?

Goldschmidt G?z, Viktória,Nagy, Adrienn,Farkas, Viktor,Keszei, Ern?,Perczel, András

, p. 30720 - 30728 (2019/10/28)

Nowadays, in Solid Phase Peptide Synthesis (SPPS), being either manual, automated, continuous flow or microwave-assisted, the reaction with various coupling reagents takes place via in situ active ester formation. In this study, the formation and stability of these key active esters were investigated with time-resolved 1H NMR by using the common PyBOP/DIEA and HOBt/DIC coupling reagents for both α- and β-amino acids. Parallel to the amide bond formation, the hydrolysis of the α/β-active esters, a side reaction that is a considerable efficacy limiting factor, was studied. Based on the chemical nature/constitution of the active esters, three amino acid categories were determined: (i) the rapidly hydrolyzing ones (t 24 h) in solution. The current insight into the kinetics of this key hydrolysis side reaction serves as a guide to optimize the coupling conditions of α- and β-amino acids, thereby saving time and minimizing the amounts of reagents and amino acids to be used-all key factors of more environmentally friendly chemistry.

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