357404-67-2Relevant articles and documents
The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)
Cheshire, David R.,?berg, Anders,Andersson, Gunilla M.K.,Andrews, Glen,Beaton, Haydn G.,Birkinshaw, Timothy N.,Boughton-Smith, Nigel,Connolly, Stephen,Cook, Tony R.,Cooper, Anne,Cooper, Sally L.,Cox, David,Dixon, John,Gensmantel, Nigel,Hamley, Peter J.,Harrison, Richard,Hartopp, Paul,K?ck, Helena,Leeson, Paul D.,Luker, Timothy,Mete, Antonio,Millichip, Ian,Nicholls, David J.,Pimm, Austen D.,St-Gallay, Steve A.,Wallace, Alan V.
, p. 2468 - 2471 (2011)
By careful analysis of experimental X-ray ligand crystallographic protein data across several inhibitor series we have discovered a novel, potent and selective series of iNOS inhibitors exemplified by compound 8.