35746-47-5Relevant academic research and scientific papers
Hypervalent Iodine(III) Mediated Synthesis of 3-Substituted 5-Amino-1,2,4-thiadiazoles through Intramolecular Oxidative S-N Bond Formation
Mariappan, Arumugam,Rajaguru, Kandasamy,Merukan Chola, Noufal,Muthusubramanian, Shanmugam,Bhuvanesh, Nattamai
supporting information, p. 6573 - 6579 (2016/08/16)
An efficient synthesis of 3-substituted-5-arylamino-1,2,4-thiadiazoles through intramolecular oxidative S-N bond formation of imidoyl thioureas by phenyliodine(III) bis(trifluoroacetate) is reported. The protocol features a metal-free approach, broad subs
Synthesis of Thiadiazolylaminoglycosides Through Ring Contraction of Triazinoglycosides Induced by [TBA-Ox]
Kikelj, Vincent,Julienne, Karine,Chalopin, Thibaut,Gouin, Sébastien G.,Evain, Michel,Deniaud, David
, p. 1264 - 1268 (2015/08/06)
A new synthetic route to thiadiazolylaminoglycosides, by a ring expansion/ring contraction sequence of glycosyl triazines, has been developed. Two potential mechanisms of this oxidative ring contraction using [TBA-Ox] are discussed. The more plausible inv
Original ring contraction of triazine derivatives to 1,2,4-thiadiazoles
Kikelj, Vincent,Julienne, Karine,Meslin, Jean-Claude,Deniaud, David
scheme or table, p. 5802 - 5804 (2009/12/26)
The oxidation of triazines 1 is described here. While treatment with m-CPBA or DMDO led to formation of a mixture of compounds, [TBA-OX] oxidation led exclusively to thiadiazoles 2 by ring contraction reaction.
Oxidative heterocyclization using diethyl azodicarboxylate
Kihara,Kabashima,Uno,Okawara,Yamasaki,Furukawa
, p. 1020 - 1023 (2007/10/02)
The reactions of amidinothioureas, imidoylthioureas, thioacylamidines, O-methyl-1-aryl-2-thioisobiurets, and 1-aryl-isodithiobiurets with diethyl azodicarboxylate (DEAD, diethyl diazenedicarboxylate) gave the corresponding thiadiazoles by the oxidative cy
