357625-64-0

Upstream product

• 357625-68-4 {9-[5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-carbamic acid allyl ester 
• 357625-67-3 {9-[4-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-carbamic acid allyl ester 
• 102434-72-0 N²-<(allyloxy)carbonyl>-3',5'-bis-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine 
• 125138-91-2 N²-allyloxycarbonyl-2'-deoxyguanosine 

Relevant academic research and scientific papers

A facile synthesis of 5′-end solid-anchored, 3′-end free oligodeoxyribonucleotides via the (5′→3′)-elongated phosphoramidite strategy

It is demonstrated that not only N2- but also O 6-protection of the guanine base is necessary for obtaining the oligodeoxyribonucleotides in high yields and at a high purity in the solid-phase synthesis via the (5′ → 3′)-chain elongated phosphoramidite approach.