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Leucine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)-DL-alanyl)-, ethyl ester, Lis a chemical compound derived from leucine, featuring an acetyl group, an amino group, and two chloroethyl groups. This specific structure endows it with alkylating properties, making it a potent agent in the disruption of DNA and proteins within tumor cells, thereby inhibiting their growth and inducing cell death. Its ethyl ester form enhances its cellular permeability and bioavailability, which is crucial for effectively targeting cancer cells while minimizing systemic toxicity. Due to its potent cytotoxic nature, careful handling and administration are essential to prevent adverse effects.

3577-89-7

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3577-89-7 Usage

Uses

Used in Cancer Research and Chemotherapy:
Leucine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)-DL-alanyl)-, ethyl ester, Lis utilized as an alkylating agent in cancer research and chemotherapy for its ability to bind to and disrupt the structure of DNA and proteins in tumor cells. This action ultimately inhibits the growth of cancer cells and leads to their death.
Used in Pharmaceutical Development:
In the pharmaceutical industry, Leucine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)-DL-alanyl)-, ethyl ester, Lis used as a key component in the development of new anticancer drugs. Its unique structure and alkylating properties make it a promising candidate for the creation of novel therapeutic agents that can effectively target and eliminate cancer cells while reducing systemic toxicity.
Used in Drug Delivery Systems:
Leucine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)-DL-alanyl)-, ethyl ester, Lis also employed in the development of drug delivery systems to improve the bioavailability and targeting of anticancer agents. Its ethyl ester form enhances cellular permeability, allowing for more effective delivery of the compound to cancer cells and minimizing potential side effects on healthy cells.
Used in Toxicity Studies:
Due to its potent cytotoxic properties, Leucine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)-DL-alanyl)-, ethyl ester, Lis used in toxicity studies to evaluate the safety and efficacy of potential anticancer drugs. These studies are crucial in determining the appropriate dosages and administration methods to maximize therapeutic effects while minimizing adverse effects on patients.

Check Digit Verification of cas no

The CAS Registry Mumber 3577-89-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,7 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3577-89:
(6*3)+(5*5)+(4*7)+(3*7)+(2*8)+(1*9)=117
117 % 10 = 7
So 3577-89-7 is a valid CAS Registry Number.
InChI:InChI=1/C23H35Cl2N3O4/c1-5-32-23(31)21(14-16(2)3)27-22(30)20(26-17(4)29)15-18-6-8-19(9-7-18)28(12-10-24)13-11-25/h6-9,16,20-21H,5,10-15H2,1-4H3,(H,26,29)(H,27,30)/t20?,21-/m0/s1

3577-89-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Leucine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)-DL-alanyl)- , ethyl ester, L-

1.2 Other means of identification

Product number -
Other names leucine sarcolysine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3577-89-7 SDS

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