35790-08-0Relevant articles and documents
Frakefamide, an analgesic tetrapeptide: Development of a pilot-plant-scale process
Franzen, Henry M.,Bessidskaia, Galina,Abedi, Vahak,Nilsson, Anders,Nilsson, Maths,Olsson, Lars
, p. 788 - 797 (2013/09/06)
A pilot-plant-process is described where frakefamide × HCl (L-tyrosyl-D-alanyl-p-fluoro-L-phenylalanyl-L-phenylalanin-amide hydrochloride) was synthesised from its amino acid monomers in seven steps. The synthesis was performed in 70-L equipment, and the