357926-10-4

Basic information

• Product Name: 1H-Imidazole, 2-(3-fluorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-
• CAS NO: 357926-10-4
• Molecular Formula: C21H15F3N2
• Molecular Weight: 352.359
• Mol File: 357926-10-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 2-(3-fluorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 2-(3-fluorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-(357926-10-4)
• EPA Substance Registry System: 1H-Imidazole, 2-(3-fluorophenyl)-4,4-bis(4-fluorophenyl)-4,5-dihydro-(357926-10-4)

Safety Data

• Hazardous Substances Data: 357926-10-4(Hazardous Substances Data)

Upstream product

• 357925-36-1 1,1-bis(4-fluorophenyl)-1,2-ethanediamine 
• 455-68-5 methyl 3-fluorobenzoate 

Relevant articles and documents

Discovery of substituted 2,4,4-triarylimidazoline derivatives as potent and selective neuropeptide Y Y5 receptor antagonists

Novel imidazoline derivatives were discovered to be potent neuropeptide Y Y5 receptor antagonists. High-throughput screening of Merck sample collections against the human Y5 receptor resulted in the identification of 2,4,4-triphenylimidazoline (1), which had an IC50 of 54 nM. Subsequent optimization led to the identification of several potent derivatives.