357928-60-0

Upstream product

• 19234-66-3 2',3'-isopropylideneadenosine-5'-carboxylic acid 
• 39491-51-5 5'-N-methyl-2',3'-O-isopropylidenecarboxamidoadenosine 

Downstream Products

• 357928-43-9 3-{[(3aS,4S,6R,6aR)-6-(6-Benzyloxycarbonylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carbonyl]-methyl-amino}-2-diazo-3-oxo-propionic acid methyl ester 
• 357928-62-2 3-{[(3aS,4S,6R,6aR)-6-(6-Benzyloxycarbonylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carbonyl]-methyl-amino}-3-oxo-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of a new class of 5'-functionalized adenosines using a rh(ii)-catalyzed 1,3-dipolar cycloaddition.

[reaction: see text] Chemically protected adenosine was functionalized at the 5' position to generate novel dipolarophiles and mesoionic dipoles. These species were found to undergo facile 1,3-dipolar cycloaddition to afford a new series of adenosine derivatives that contain a point of diversification at the 5' position of adenosine.