357940-96-6Relevant academic research and scientific papers
Copper-Catalyzed Enantioselective 1,2-Reduction of Cycloalkenones
Shi, Yongjie,Wang, Jingxin,Yin, Qin,Zhang, Xumu,Chiu, Pauline
supporting information, p. 5658 - 5663 (2021/08/01)
We report an asymmetric 1,2-reduction of cyclic α,β-unsaturated ketones to access various enantiomerically enriched cyclic allylic alcohols under mild conditions, catalyzed by in situ generated copper hydride ligated with (R)-DTBM-C3*-TunePhos. α-Brominated cycloalkenones were reduced with excellent enantioselectivities of up to 98% ee, while substrates that were without α-substituents were reduced chemoselectively, with moderate enantioselectivities.
A Pd(II)-catalyzed ring-expansion reaction of cyclic 2-azidoalcohol derivatives: Synthesis of azaheterocycles
Chiba, Shunsuke,Xu, Yan-Jun,Wang, Yi-Feng
supporting information; experimental part, p. 12886 - 12887 (2009/12/06)
(Chemical Equation Presented) A Pd(II)-catalyzed ring expansion-reaction of cyclic 2-azidoalcohol derivatives was found to proceed via an unprecedented C-C bond cleavage-C-N bond formation sequence, providing substituted azaheterocycles.
