357952-89-7Relevant academic research and scientific papers
METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES
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Page/Page column 33, (2008/12/05)
Optically active 2-sulfonyloxy-1-phenylethanol derivative of formula (II) can be prepared easily and selectively by the method of the present invention using an asymmetric reduction of an α-sulfonyloxy acetophenone compound with a rhodium catalyst having petamethylcyclopentadienyl group and a hydrogen donor, and the compound of formula (II) obtained in the inventive method exhibits a higher e.e. (enantiomer excess) value than that of the products in the conventional methods.
Convenient synthesis of optically active 1,2-diol monosulfonates and terminal epoxides via oxazaborolidine-catalyzed asymmetric borane reduction of α-sulfonyloxy ketones
Cho, Byung Tae,Yang, Weon Ki,Choi, Ok Kyung
, p. 1204 - 1211 (2007/10/03)
A very convenient asymmetric synthesis of 1,2-diol monosulfonates and terminal epoxides with high optical purity via oxazaborolidine-catalyzed asymmetric borane reduction of α-sulfonyloxy ketones using N-ethyl-N-isopropylaniline-borane complex as borane carrier has been developed.
A new class of chiral modifiers for the enantioselective hydrogenation of α-ketoesters with Pt/Al2O3
Simons,Wang,Heinz,Giger,Mallat,Pfaltz,Baiker
, p. 505 - 518 (2007/10/02)
A series of enantiomerically pure chiral amino alcohols have been synthesized and applied as modifiers in the enantioselective hydrogenation of ethyl pyruvate over supported Pt catalysts. Their use enabled an enantiomeric excess of up to 75%. A molecular modelling study of the modifiers and reactant on a Pt(111) surface provides explanation for the observed enantiodifferentiation.
