357958-77-1Relevant academic research and scientific papers
Efficient introduction of protected guanidines in boc solid phase peptide synthesis.
Zhang,Kennan
, p. 2341 - 2344 (2001)
[reaction: see text] Reaction of primary amines with pyrazole 1 results in rapid and efficient guanidinylation, either in solution or on solid phase. The reaction affords sulfonamide-protected products required for BOC solid phase peptide synthesis (SPPS)
