3580-89-0Relevant academic research and scientific papers
Visible-Light-Induced Radical Defluoroborylation of Trifluoromethyl Alkenes: An Access to gem-Difluoroallylboranes
Chen, Guojun,Wang, Liling,Liu, Xiaozu,Liu, Peijun
supporting information, p. 2990 - 2996 (2020/06/10)
A photoredox-catalyzed defluoroborylation of trifluoromethyl alkenes with N-heterocyclic carbene boranes is described for the synthesis of gem-difluoroallylboranes. This protocol exhibits a broad substrate scope and good functional group compatibility, which enables the late-stage functionalization of structurally complex compounds. Further transformations of the defluoroborylation products to valuable CF2-containing molecules are also demonstrated. (Figure presented.).
Synthesis of gem-Difluoroallylboronates via FeCl2-Catalyzed Boration/β-Fluorine Elimination of Trifluoromethyl Alkenes
Liu, Yang,Zhou, Yuhan,Zhao, Yilong,Qu, Jingping
supporting information, p. 946 - 949 (2017/02/26)
The first ferrous chloride catalyzed boration/β-fluorine elimination of trifluoromethyl alkenes is described. Thus, a full range of gem-difluoroallylboronates were obtained in high yield under mild conditions. As an important fluorinated building block, gem-difluoroallylboronate can be readily converted into diverse difluoro-substituted species.
REACTIONS EN MILIEU HETEROGENE SOLIDE-LIQUIDE FAIBLEMENT HYDRATE: II - LA REACTION DE WITTIG DANS LES SYSTEMES CARBONATES ALCALINS/SOLVANT ORGANIQUE APROTIQUE
Bigot, Yves Le,Delmas, Michel,Gaset, Antoine
, p. 339 - 350 (2007/10/02)
The use of alkaline carbonates in a slighty hydrated solid-liquid aprotic organic media allowed the synthesis of alkenes from polyfunctionnal aldehydes or activated ketones with high yield in a Z preferential stereochemistry.The reaction mechanism proposed takes in account the specific use of water on the solvation of cationic species at the solid-liquid interface to explain the Z.E alkene ratio.
