35802-05-2Relevant academic research and scientific papers
Hypervalent Iodine(III)-Catalyzed Epoxidation of β-Cyanostyrenes
Mangaonkar, Saeesh R.,Singh, Fateh V.
, p. 4473 - 4486 (2019)
A convenient approach for the synthesis of β-cyanoepoxides is illustrated by iodine(III)-catalyzed epoxidation of electron-deficient β-cyanostyrenes, wherein the active catalytic iodine(III) species was generated in situ. The epoxidation of β-cyanostyrenes was performed using 10 molpercent PhI as precatalyst in the presence of 2.0 equivalents Oxone as an oxidant and 2.4 equivalents of TFA as an additive at room temperature under ultrasonic radiations. The β-cyanoepoxides were isolated in good to excellent yields in a short reaction time.
