35804-09-2

Upstream product

• 25917-49-1 1-(4-chlorophenyl)-2-(p-tolylsulfonyloxy)ethanone 
• 104-94-9 4-methoxy-aniline 
• 99-91-2 para-chloroacetophenone 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 118985-12-9 p-chlorophenacyl m-nitrobenzenesulphonate 
• 118985-11-8 p-chlorophenacyl p-chlorobenzenesulphonate 
• 115400-12-9 p-chlorophenacyl benzenesulphonate 

Downstream Products

• 155699-84-6 [2-(4-Chloro-phenyl)-2-oxo-ethyl]-(4-methoxy-phenyl)-thiocarbamic acid O-phenyl ester 
• 705972-11-8 N₁-[2-(4-chlorophenyl)-2-oxoethyl]-N₁-(4-methoxyphenyl)-2-phenylacetamide 
• 1089733-83-4 C₁₆H₁₂ClNO 
• 1189054-21-4 C₂₁H₂₀ClNO₅ 
• 1189054-22-5 C₂₃H₂₄ClNO₅ 
• 1374162-46-5 1-(4-chlorophenyl)-2-[(4-methoxyphenyl)({[2-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl})amino]ethan-1-one 
• 1374162-60-3 (R)-4-(4-chlorophenyl)-2-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinolin-4-ol 

Relevant academic research and scientific papers

Sequential One-Pot Synthesis of Imidazoles and 2H-Imidazolones from β-Ketoamines, Acylating Agents and Ammonium Acetate

An efficient, practical, straight forward, and transition metal-free three-component synthesis of diversely substituted imidazoles and 2H-imidazolones from β-ketoamines, acylating agents, and ammonium acetate has been described herein. This approach invol

Synthesis, Characterization, and Antibacterial Activity of Some Novel Substituted Imidazole Derivatives via One-pot Three-Component

A simple and highly efficient one-pot, three-component synthesis of novel substituted imidazole derivatives has been reported by the reaction of 3-(2-bromoacetyl)-2H-chromen-2-one, ammonium thiocyanate, and phenacyl aniline in the presence of acetic acid

Synthesis, antibacterial activity and binding mode analysis of some novel 1,4-diaryl imidazole thiones

A novel series of fifteen diaryl imidazole thiones 2a-o was synthesized by reacting the corresponding 1-(aryl)-2-(arylamino)-ethanones 1 with ammonium thiocyanate. The compounds have been characterized on the basis of elemental analysis and spectral data.

A rapid and direct access to symmetrical/unsymmetrical 3,4-diarylmaleimides and pyrrolin-2-ones

1,8-Diazabicyclo[5.4.0]undec-7ene (DBU) facilitated the oxidative cyclization of phenacyl amide in the presence of atmospheric oxygen under environmentally friendly conditions. The reaction has been studied under various conditions and a plausible mechani

PREPARATION OF NEW THIOHYDROXAMIC ACID DERIVATIVES: SYNTHESIS OF SUBSTITUTED 1-HYDROXY-1,2-DIHYDROIMIDAZOLE-2-THIONES

A general method for the synthesis of the title compounds is reported.The N-phenacylarylamines (11), prepared from the corresponding phenacyl bromides (9) and arylamines (10), give the thiono (or dithio) carbamates (12) on treatment with phenoxythionocarb

Hypervalent iodine mediated syntheses of heterocycles: One-pot facile syntheses of 1,4-diaryl-2-mercaptoimidazoles, 2-(α-anilinoacetyl)thiophenes and 1-aryl-2-mercapto-4-(2-thienyl)imidazoles from aryl/2-thienyl methyl ketones

Successive treatment of acetophenones (1a-e) or 2-acetylthiophene (4) with benzene, appropriate aniline and KSCN/AcOH leads to the formation of 1,4-diaryl-2-mercaptoimidazoles (3aa-3ea) or 1-aryl-2-mercapto-4-(2-thienyl)imidazoles (6a-f) respectively.This procedure also provides 2(α-anilinoacetyl)thiophenes (5a-f) in one pot from 4.

Nucleophilic Substitution Reactions of Phenacyl Benzenesulphonates with Anilines in Methanol-Acetonitrile Mixtures

The nucleophilic substitution reactions of phenacyl benzenesulphonates with anilines in methanol-acetonitrile have been studied.A stronger nucleophile was found to cause less bond cleavage, while a better leaving group led to less bond formation, in compl