3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone is a steroidal compound and a derivative of cholic acid, characterized by its γ-lactone structure that features a carbonyl group conjugated with a double bond. This organic compound holds potential in the pharmaceutical domain due to its capacity to modulate cholesterol and lipid metabolism, along with its potential roles in treating liver diseases and exhibiting anti-inflammatory and immunomodulatory effects. Furthermore, it serves as a valuable precursor in the synthesis of additional steroidal derivatives with therapeutic applications.
35833-72-8
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Basic information
- Product Name: 3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone
- Synonyms: 3α,20-Dihydroxy-18,25,26,27-tetranor-5α-dammaran-24-oic acid 24,20-lactone;3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone;Cabralea hydroxylactone;Cabraleahydroxylactone;3-Epicabraleahydroxylactone
- CAS NO:35833-72-8
- Molecular Formula: C27H44O3
- Molecular Weight: 416.65
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: 155-157 °C
- Boiling Point: 518.7±23.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.061±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 15.18±0.70(Predicted)
- CAS DataBase Reference: 3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone(CAS DataBase Reference)
- NIST Chemistry Reference: 3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone(35833-72-8)
- EPA Substance Registry System: 3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone(35833-72-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 35833-72-8(Hazardous Substances Data)
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35833-72-8 Usage
Uses
Used in Pharmaceutical Industry:3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone is utilized as a cholesterol and lipid metabolism regulator for its potential to influence key pathways involved in lipid homeostasis, thereby impacting conditions related to dyslipidemia and cardiovascular health.
Used in Liver Disease Treatment:
Within the healthcare sector, 3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone is applied in the treatment of liver diseases, leveraging its potential to ameliorate hepatic functions and address specific liver-related conditions, possibly including those associated with cholesterol gallstone formation or other liver dysfunctions.
Used in Anti-inflammatory and Immunomodulatory Applications:
3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone is harnessed for its anti-inflammatory and immunomodulatory properties, making it a candidate for the development of therapeutics aimed at reducing inflammation and modulating immune responses in various pathological conditions.
Used as a Precursor in Organic Synthesis:
In the chemical and pharmaceutical industries, 3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone serves as a crucial precursor for the synthesis of other steroidal derivatives, which may possess enhanced therapeutic potential or be tailored for specific medical applications, expanding the range of available treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 35833-72-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,8,3 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.Calculate Digit Verification of CAS Registry Number 35833-72:
(7*3)+(6*5)+(5*8)+(4*3)+(3*3)+(2*7)+(1*2)=128
128 % 10 = 8
So 35833-72-8 is a valid CAS Registry Number.
35833-72-8Upstream product
35833-72-8Downstream Products
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3α,20-Dihydroxy-4,4,14-trimethyl-18-nor-5α-cholan-24-oic acid γ-lactone
