358343-48-3

Upstream product

• 100-19-6 (4-nitrophenyl)ethanone 
• 1571-08-0 methyl 4-formylbenzoate 

Downstream Products

• 1346136-02-4 methyl 4-[3-(4-aminophenyl)propyl]benzoate 
• 1346136-04-6 methyl 4-(3-{4-[(cyanoacetyl)amino]phenyl}propyl)benzoate 
• 1346136-08-0 methyl 4-[3-(4-{[cyano(cyclohexylidene)acetyl]amino}phenyl)propyl]benzoate 
• 1346136-09-1 methyl 4-[3-(4-{[(2-amino-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)carbonyl]amino}phenyl)propyl]benzoate 
• 1346136-10-4 methyl 4-[3-(4-{[(2-{[3-(chlorosulfonyl)benzoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)carbonyl]amino}phenyl)propyl]benzoate 

Relevant academic research and scientific papers

AMINOALKYL-SUBSTITUTED N-THIENYL BENZAMIDE DERIVATIVE

[Problem] To provide a compound that has an intestinal phosphate transporter (NPT-IIb) inhibitory action and is useful as an active ingredient of an agent for treating and/or preventing hyperphosphatemia. [Means for Solution] The present inventors conduct

TETRAHYDROBENZOTHIOPHENE COMPOUND

The purpose is to provide a compound which has an intestinal phosphate transporter (NPT-IIb) inhibitory action and is useful as an active ingredient of an agent for treating and/or preventing hyperphosphatemia. A tetrahydrobenzothiophene compound of the following formula (I) has NPT-IIb inhibitory action and can be used as an agent for treating and/or preventing hyperphosphatemia: wherein, R1 represents -O-lower alkyl, -lower alkylene-phenyl, or the like; R2 and R3 are the same as or different from each other and represent H, lower alkyl, cycloalkyl, aryl, heteroaryl or the like, or, R2 and R3 may be combined with a nitrogen atom to which they bind to form 5- to 7-membered saturated cyclic amino; R4,s are the same as or different from each other and represent halogen, lower alkyl; and n represents 0 to 2.