358376-25-7Relevant academic research and scientific papers
A stereochemical study of optically active thiazolidines
Cruz, Alejandro,Vasquez-Badillo, Aurora,Ramos-Garcia, Iris,Contreras, Rosalinda
, p. 711 - 717 (2007/10/03)
We report a stereochemical study of a series of free N-H and N-methylated 1,3-thiazolidines bearing H or CH3 at C-(2). These compounds were readily prepared from ephedrine and pseudoephedrines. The stereochemistry of the compounds under study was deduced using 1H and 13C NMR spectroscopy. Two isomers were found for compounds having a methyl group at C-(2) (i.e. C-(2)HCH3); interconversion of these isomers, presumably via a non-cyclic zwitterionic intermediate, was observed.
