35852-74-5Relevant articles and documents
Palladium-Catalyzed Dehydrative Cross-Coupling of Allylic Alcohols and N-Heterocycles Promoted by a Bicyclic Bridgehead Phosphoramidite Ligand and an Acid Additive
Kang, Kyungjun,Kim, Jaewook,Lee, Ansoo,Kim, Woo Youn,Kim, Hyunwoo
supporting information, p. 616 - 619 (2016/02/18)
A mild and efficient dehydrative cross-coupling reaction between allylic alcohols and N-heterocycles using palladium catalysis is reported. A bicyclic bridgehead phosphoramidite (briphos) ligand together with Pd(dba)2 is a highly efficient catalyst, and an acid additive involved in the rate-determining step promotes the catalytic cycle. The coupling reaction of allylic alcohols with N-heterocycles including imidazoles, benzimidazoles, and triazole proceeds under mild reaction conditions with high yields using Pd/briphos and pentafluorophenol.
Synthesis of heterocyclic compounds from 4-formylpyrazoles
Mortikov,Rodinovskaya,Fedorov,Shestopalov,Belyakov
, p. 443 - 456 (2015/02/02)
Formylation of pyrazole and 2,5-dimethylpyrazole gave a number of pyrazole-containing aldehydes, which can be used to obtain chromenes, tetrahydrochromenes, 1,4-dihydropyrano[2,3-c]pyrazoles, pyrano[3,2-c]chromenes, thiochromeno[4,3-b]pyrans, pyrano[3,2-c
Synthesis and reactions of the first allenyl azo compounds
Banert, Klaus,Hagedorn, Manfred,Schlott, Jana
, p. 360 - 361 (2007/10/03)
Several propargylhydrazines were prepared and then oxidized by manganese dioxide to generate short-lived 1,1-diazenes, which produced novel allenyl azo compounds (8) through [2,3] sigmatropic rearrangement. Isomerization of 8 or nucleophilic addition to the title compounds lead to hydrazones as well as pyrazole derivatives.
One-pot synthesis of pharmacologically active diamines via rhodium- catalysed carbonylative hydroaminomethylation of heterocyclic allylic amines
Rische, Thorsten,Mueller, Kai-Sven,Eilbracht, Peter
, p. 9801 - 9816 (2007/10/03)
Pharmacologically active derivatives of phenothiazine, iminodibenzyl, carbazole and pyrazole are prepared with high yields and chemoselectivity by the reaction of the corresponding N-allylic or N-methallylic compounds, primary or secondary amines, carbon monoxide and hydrogen in the presence of [Rh(cod)Cl]2 as catalyst via a one pot hydroformylation - amine condensation - reduction sequence.
Selective Allylation and Propargylation of Azoles by Phase Transfer Catalysis in the Absence of Solvent
Diez-Barra, Enrique,Hoz, Antonio de la,Loupy, Andre,Sanchez-Migallon, Ana
, p. 1367 - 1374 (2007/10/02)
Phase transfer catalysis without solvent allows the selective preparation of N-allyl- and N-propargylazoles or N-(1-propenyl)- and N-(1,2-propadienyl)azoles by reaction of the parent azole with allyl or propargyl bromides.Small variations in the reaction conditions, base or temperature, afford the desired selectivity.
Synthesis of N-Alkylpyrazoles by Phase Transfer Catalysis without Solvent
Diez-Barra, E.,Hoz, A. de la,Sanchez-Migallon, A.,Tejeda, J.
, p. 2849 - 2853 (2007/10/02)
The alkylation of pyrazole is performed by phase transfer catalysis without solvent.High yields of N-alkylpyrazoles are obtained and the principal problems in the alkylation are suitably solved.
ETUDE DANS LA SERIE DES ORGANOSILYLAZOLES I. ACTION DES HALOGENURES D'ALKYLE, DES CHLORURES D'ACIDE ET DES CETONES HALOGENEES
Gasparini, J. P.,Gassend, R.,Maire, J. C.,Elguero, J.
, p. 141 - 150 (2007/10/02)
The reactivity of organosilylamines of imidazole, pyrazole, 1,2,4-triazole and benzotriazole towards alkyl halides, acidic chlorides and halogenated ketones has been studied.Except for 1-trimethylsilylimidazole, which gives a mixed quaternary salt, reactions with primary halides lead to the corresponding 1-alkylated heterocyclic compounds in high yields; in each case only one isomer is obtained (1-alkyl-1,2,4-triazole and 1-alkylbenzotriazole).Similarly acidic chlorides give 1-acylated derivatives in quantitative yields.Finally α- or β-halogenated ketones show different behaviour and give the addition or substitution products.
