358616-33-8Relevant academic research and scientific papers
Mapping serum albumin adducts of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine by data-dependent tandem mass spectrometry
Peng, Lijuan,Dasari, Surendra,Tabb, David L.,Turesky, Robert J.
, p. 2179 - 2193 (2013/01/15)
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a heterocyclic aromatic amine that is formed during the cooking of meats. PhIP is a potential human carcinogen: it undergoes metabolic activation to form electrophilic metabolites that bind to DNA
Synthesis of deuterated 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine (PhIP) and its N-hydroxy derivative
Tanga, Mary J.,Bupp, James E.,Bradford, Wallace W.
, p. 405 - 411 (2007/10/03)
The syntheses of the deuterium-labeled food mutagen 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine (PhIP) and its N-hydroxy metabolite are described. Unlabeled PhIP is deuterated using a boron trifluoride phosphoric acid complex in one step. Labeled
