358730-97-9 Usage
Uses
Used in Research Applications:
Tetradecanoic-12-d1 Acid is used as an isotopically labeled research compound for investigating metabolic pathways, enzyme activities, and lipid metabolism. The deuterium labeling allows for the differentiation between the labeled compound and its endogenous counterparts, providing insights into the mechanisms and dynamics of biological systems.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Tetradecanoic-12-d1 Acid serves as a valuable tool for drug development and screening. Its isotopically labeled nature enables researchers to study the interactions between the compound and target proteins or enzymes, aiding in the design and optimization of new drugs.
Used in Analytical Chemistry:
Tetradecanoic-12-d1 Acid is employed in analytical chemistry for the development and validation of analytical methods, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. The deuterium labeling enhances the detection and quantification of the compound, improving the accuracy and reliability of the analytical techniques.
Used in Nutritional Studies:
In nutritional research, Tetradecanoic-12-d1 Acid can be used to study the absorption, distribution, metabolism, and excretion of fatty acids in the human body. The isotopically labeled compound allows for the tracking of its metabolic fate, providing valuable information on the role of fatty acids in health and disease.
Check Digit Verification of cas no
The CAS Registry Mumber 358730-97-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,8,7,3 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 358730-97:
(8*3)+(7*5)+(6*8)+(5*7)+(4*3)+(3*0)+(2*9)+(1*7)=179
179 % 10 = 9
So 358730-97-9 is a valid CAS Registry Number.
358730-97-9Relevant academic research and scientific papers
Total synthesis of perdeuterated phospholipids
Bersch, B.,Starck, J. P.,Milon, A.,Nakatani, Y.,Ourisson, G.
, p. 575 - 583 (2007/10/02)
A general method for the total synthesis of various perdeuterated phospholipids (DMPA, DMPG, DMPE, DMPC) is described.Starting from simple and easily obtainable deuterated precursors, perdeuterated phosphatidic acid (DMPA-d59) was synthesized.DMPA-d59 was coupled to various perdeuterated alcohols in the presence of alkylsulfonyl chlorides as condensing agents.The preparation of the perdeuterated alcohols is also presented.The major advantage of this method lies in the independent synthesis of DMPA and the alcohol moieties, allowing the transformation to the desired phospholipid class in the final reaction step.The reaction scheme presented here can also be used for the synthesis of selectively deuterated phospholipids.Keywords - perdeuterated phospholipids / phosphatidic acid-d59 / phosphatidylglycerol-d64 / phosphatidylcholine-d72 / phopshatidylethanolamine-d63 / total synthesis
