35880-74-1

Upstream product

• 176512-40-6 3-Methyl-4-(2-methyl-4-nitro-benzenesulfonyl)-phenylamine 
• 855939-45-6 bis-(4-acetylamino-2-methyl-phenyl)-sulfoxide 
• 537-92-8 3-Methylacetanilide 
• 176512-33-7 2,2'-dimethyl-4-N-tosylamino-4'-nitrodiphenyl sulfone 
• 176512-24-6 4-Methyl-N-[3-methyl-4-(2-methyl-4-nitro-phenylsulfanyl)-phenyl]-benzenesulfonamide 
• 855939-53-6 bis-(4-acetylamino-2-methyl-phenyl)-sulfone 

Downstream Products

• 132653-96-4 bis-(4-chloro, 2-methylphenyl) sulphone 

Relevant academic research and scientific papers

New antifolate 4,4'-diaminodiphenyl sulfone substituted 2,4-diamino-5-benzylpyrimidines. Proof of their dual mode of action and autosynergism

New 4,4'-diaminodiphenylsulfone substituted 2,4-diamino-5-benzylpyrimidines were synthesized. These compounds are highly active inhibitors of both bacterial dihydrofolate reductase (DHFR) and dihydropteroic acid synthase (SYN). The simultaneous inhibition