3,7-Dichloro-5-[3-(dimethylamino)propyl]-5H-dibenz[b,f]azepine, also known as Clozapine, is a tricyclic dibenzodiazepine derivative with antipsychotic properties. It is primarily used in the treatment of schizophrenia, particularly in cases where other antipsychotic medications have been ineffective. Clozapine has a unique chemical structure that allows it to bind to various neurotransmitter receptors, including dopamine, serotonin, and norepinephrine, which contributes to its effectiveness in managing both positive and negative symptoms of schizophrenia. However, it is also associated with potential side effects, such as agranulocytosis, a severe reduction in white blood cells, which necessitates regular blood monitoring for patients on this medication.
3589-23-9
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Basic information
- Product Name: 3,7-Dichloro-5-[3-(dimethylamino)propyl]-5H-dibenz[b,f]azepine
- Synonyms: 3,7-Dichloro-5-[3-(dimethylamino)propyl]-5H-dibenz[b,f]azepine
- CAS NO:3589-23-9
- Molecular Formula: C19H20Cl2N2
- Molecular Weight: 347.2815
- EINECS: N/A
- Product Categories: N/A
- Mol File: 3589-23-9.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 475.9°Cat760mmHg
- Flash Point: 241.6°C
- Appearance: /
- Density: 1.212g/cm3
- Vapor Pressure: 3.19E-09mmHg at 25°C
- Refractive Index: 1.602
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 3,7-Dichloro-5-[3-(dimethylamino)propyl]-5H-dibenz[b,f]azepine(CAS DataBase Reference)
- NIST Chemistry Reference: 3,7-Dichloro-5-[3-(dimethylamino)propyl]-5H-dibenz[b,f]azepine(3589-23-9)
- EPA Substance Registry System: 3,7-Dichloro-5-[3-(dimethylamino)propyl]-5H-dibenz[b,f]azepine(3589-23-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 3589-23-9(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 3589-23-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,8 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.Calculate Digit Verification of CAS Registry Number 3589-23:
(6*3)+(5*5)+(4*8)+(3*9)+(2*2)+(1*3)=109
109 % 10 = 9
So 3589-23-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H20Cl2N2/c1-22(2)10-3-11-23-18-12-16(20)8-6-14(18)4-5-15-7-9-17(21)13-19(15)23/h4-9,12-13H,3,10-11H2,1-2H3
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3,7-Dichloro-5-[3-(dimethylamino)propyl]-5H-dibenz[b,f]azepine
