359010-51-8

Basic information

• Product Name: 2-(4-Sulphamoylanilino)-4-(4-methoxyphenoxy)-5-chloropyrimidine
• Synonyms: 2-(4-Sulphamoylanilino)-4-(4-methoxyphenoxy)-5-chloropyrimidine
• CAS NO: 359010-51-8
• Molecular Weight: 406.849
• Mol File: 359010-51-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-Sulphamoylanilino)-4-(4-methoxyphenoxy)-5-chloropyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Sulphamoylanilino)-4-(4-methoxyphenoxy)-5-chloropyrimidine(359010-51-8)
• EPA Substance Registry System: 2-(4-Sulphamoylanilino)-4-(4-methoxyphenoxy)-5-chloropyrimidine(359010-51-8)

Safety Data

• Hazardous Substances Data: 359010-51-8(Hazardous Substances Data)

Upstream product

• 358978-09-3 2,5-Dichloro-4-(4-methoxy-phenoxy)-pyrimidine 
• 63-74-1 sulfanilamide 

Relevant articles and documents

Pyrimidine compounds

Pyrimidine derivatives of formula (I) wherein: Q1 and Q2 are independently selected from aryl or carbon linked heteroaryl optionally substituted as defined within; and one of Q1 and Q2 or both Q1 and Q2 is substituted on a ring carbon by one group selected from sulphamoyl, N—(C1-4alkyl)sulphamoyl (optionally substituted by halo or hydroxy), N,N-di-(C1-4alkyl)sulphamoyl (optionally substituted by halo or hydroxy), C1-4alkylsulphonyl (optionally substituted by halo or hydroxy) or a substituent of the formula (Ia) or (Ia′): wherein Q1, Q2, G, R1, Y, Z, Q3, n and m are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) inhibitors are also described.