359015-31-9

Upstream product

• 5470-84-8 4-benzyloxybutanal 
• 359015-17-1 (2S,3R)-6-benzyloxy-3-tert-butoxycarbonylamino-2-hydroxy-hexanoic acid 
• 133407-67-7 ethyl (E)-6-(benzyloxy)hex-2-enoate 
• 4541-14-4 4-benzyloxy-butan-1-ol 

Downstream Products

• 359015-21-7 (2S,3R)-2-Azido-6-benzyloxy-3-tert-butoxycarbonylamino-hexanoic acid ethyl ester 
• 124831-37-4 cis-4-oxo-3-[(phenoxyacetyl)amino]-2-azetidinepropanoic acid 
• 359015-23-9 (3S,4R)-3-Azido-4-(3-benzyloxy-propyl)-azetidin-2-one 
• 359015-25-1 N-[(2R,3S)-2-(3-Benzyloxy-propyl)-4-oxo-azetidin-3-yl]-2-phenoxy-acetamide 

Relevant academic research and scientific papers

An asymmetric aminohydroxylation approach to the stereoselective synthesis of cis-substituted azetidinone of loracarbef

A formal synthesis of loracarbef is described. The required key cis-substituted azetidinone skeleton was stereoselectively constructed via β-amino acid, which was provided from the asymmetric aminohydroxylation of α,β-unsaturated ester.