35919-98-3

Upstream product

• 2757-83-7 1-methylalloxan 
• 68874-23-7 N-o-tolyl-o-phenylenediamine 
• 52753-16-9 10-o-tolyl-10H-benzo[g]pteridine-2,4-dione 
• 74-88-4 methyl iodide 
• 95-53-4 o-toluidine 
• 4318-56-3 3-methyl-6-chlorouracil 
• 133373-55-4 3-Methyl-6-o-tolylamino-1H-pyrimidine-2,4-dione 
• 586-96-9 Nitrosobenzene 

Relevant academic research and scientific papers

A new and improved N-3 alkylation of 10-substituted isoalloxazines using 1,8-diazabicyclo[5.4.0]undec-7-ene in benzene

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) has been identified as a remarkable base for the alkylation at N-3 position of 10-substituted isoalloxazines with alkyl halides in dry benzene.

Microwave-assisted synthesis of 10-substituted isoalloxazines in the presence of solid acids

The microwave-enhanced synthesis of 10-substituted isoalloxazines is achieved rapidly (～4 min) and in good yield (>80-95%) via the cyclocondensation of 2-substituted aminoanilines with alloxan or N-methylalloxan monohydrate in the presence of acidic alumi

Flavins as potential antimalarials. 2. 3-Methyl-10-(substituted-phenyl)flavins

A series of 3-methyl-10-(substituted-phenyl)flavins was prepared and tested for antimalarial activity against the lethal parasite Plasmodium vinckei in mice. Several of these analogues were found to be effective antimalarial agents. A quantitative structure-activity relationship study was undertaken with 44 analogues and no satisfactory relationship could be established.