35921-73-4Relevant academic research and scientific papers
Amberlyst-15 in ionic liquid: An efficient and recyclable reagent for nucleophilic substitution of alcohols and hydroamination of alkenes
Qureshi, Ziyauddin S.,Deshmukh, Krishna M.,Tambade, Pawan J.,Dhake, Kishor P.,Bhanage, Bhalchandra M.
experimental part, p. 6233 - 6238 (2010/12/25)
The nucleophilic substitution reaction of secondary alcohols and hydroamination of alkenes with amides, sulfonamides, carbamates, and amines using Amberlyst-15 immobilized in [Bmim][BF4] (1-butyl-3- methylimidazolium tetrafluoroborate) ionic liquid as an efficient recyclable reagent is described. The solvent effect is prominent in the reaction, and the desired substitution products are obtained in good to excellent yield. The protocol is advantageous due to the ease of handling of the reagents, the simple work-up procedure, and the environmentally benign conditions that allow effective recyclability. A facile protocol involving Amberlyst-15 in the ionic liquid [Bmim][BF4] (= 1-butyl-3-methylimidazolium tetrafluoroborate) has been developed for nucleophilic substitution of alcohols and hydroamination of alkenes.
Phosphotungstic acid catalyzed amidation of alcohols
Wang, Guan-Wu,Shen, Ye-Bing,Wu, Xue-Liang
experimental part, p. 4367 - 4371 (2009/04/14)
Mild nucleophilic substitution reactions of benzhydrylic, benzylic, allylic, and simple aliphatic alcohols with sulfonamides, benzamide, and 4-nitroaniline in the presence of 12-phosphotungstic acid as an efficient, eco-friendly, cheap, and air- and moisture-tolerant catalyst for the construction of C-N bonds has been investigated. The amine derivatives were obtained in good yields (up to 98%). The reusable nature of the 12-phosphotungstic acid makes this protocol more attractive. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Phosphinite- and phosphite-based type I palladacycles as highly active catalysts for addition reactions of arylboronic acids with aldehydes, α,β-unsaturated ketones, α-ketoesters, and aldimines
He, Ping,Lu, Yong,Hu, Qiao-Sheng
, p. 5283 - 5288 (2008/02/09)
Phosphinite- and phosphite-based type I palladacycle-catalyzed additions of arylboronic acids with aldehydes, α,β-unsaturated ketones, α-ketoesters, and aldimines are described. Our study showed that readily available phosphinite- and phosphite-based type I palladacycles could possess higher catalytic activity than phosphine-based palladacycles and were highly active, practical catalysts. Our study may pave the road for development of optically active phosphinite- and phosphite-based palladacycles for asymmetric catalysis.
THE MECHANISM OF HYDROXYLATION OF ORGANOMETALLIC REAGENTS BY 2-SULFONYLOXAZIRIDINES
Davis, Franklin A.,Wei, Jia,Sheppard, Aurelia C.,Gubernick, Steven
, p. 5115 - 5118 (2007/10/02)
The hydroxylation of organometallic reagents (RM) by 2-sulfonyloxaziridines 1 is shown to involve a hemiaminal intermediate 2, whose stability is apparently related to the nucleophilicity of the hydroxylated product (ROH).
