359405-40-6

Basic information

• Product Name: Methyl 3α-{[3-(tert-butoxycarbonylamino)propylamino]thioxomethylamino}-7α-hydroxy-12α-phenylaminocarbonyloxy-5β-cholan-24-oate
• CAS NO: 359405-40-6
• Molecular Weight: 757.048
• Mol File: 359405-40-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methyl 3α-{[3-(tert-butoxycarbonylamino)propylamino]thioxomethylamino}-7α-hydroxy-12α-phenylaminocarbonyloxy-5β-cholan-24-oate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3α-{[3-(tert-butoxycarbonylamino)propylamino]thioxomethylamino}-7α-hydroxy-12α-phenylaminocarbonyloxy-5β-cholan-24-oate(359405-40-6)
• EPA Substance Registry System: Methyl 3α-{[3-(tert-butoxycarbonylamino)propylamino]thioxomethylamino}-7α-hydroxy-12α-phenylaminocarbonyloxy-5β-cholan-24-oate(359405-40-6)

Safety Data

• Hazardous Substances Data: 359405-40-6(Hazardous Substances Data)

Upstream product

• 359405-39-3 Methyl 3α-(N-tert-butoxycarbonylamino)-7α-hydroxy-12α-phenylaminocarbonyloxy-5β-cholan-24-oate 
• 286955-45-1 (3-isothiocyanatopropyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Steroidal guanidines as enantioselective receptors for N-acyl α-amino acids. Part 1. 3α-Guanylated carbamates derived from cholic acid

Receptors 5-11, bearing guanidinium, carbamate and (in some cases) other functional groups, were synthesized from cholic acid 1. These cations were shown to extract chiral carboxylate anions from aqueous buffer into chloroform with significant enantioselectivities. The most successful receptors bore two carbamate substituents and achieved, in the best cases, ratios (L:D) of 7-10:1 for a series of five N-acetyl α-amino acids.