359407-93-5

Upstream product

• 359407-89-9 (3'E,6'R)-2,4-dimethyoxy-6-(6'-benzyloxy-hept-3'-enyl)benzoic acid 
• 359407-86-6 (R)-2,4-dimethyoxy-6-(6-hydroxyheptyl)benzoic acid 
• 359407-90-2 (R)-2,4-dimethoxy-7-methyl-7,8,9,10,11,12-hexahydro-6-oxa-benzocyclodecen-5-one 
• 359407-88-8 (2E,5R)-5-benzyloxy-1-bromo-2-hexene 
• 171087-09-5 (2E,5R)-5-benzyloxy-2-hexen-1-ol 
• 100-44-7 benzyl chloride 
• 359407-92-4 (R)-2,4-dihydroxy-7-methyl-7,8,9,10,11,12-hexahydro-6-oxa-benzocyclodecen-5-one 

Downstream Products

• 359407-96-8 isobutyl (R)-2,4-dibenzyloxy-6-(6-hydroxyheptyl)benzoate 
• 359407-95-7 ethyl (R)-2,4-dibenzyloxy-6-(6-hydroxyheptyl)benzoate 
• 359407-94-6 (R)-2,4-dibenzyloxy-6-(6-hydroxyheptyl)benzoic acid 

Relevant academic research and scientific papers

Syntheses of β-resorcylic acid derivatives, novel potato micro-tuber inducing substances isolated from Lasiodiplodia theobromae

The syntheses of β-resorcylic acid derivatives 1 and 2, isolated from fungus Lasiodiplodia theobromae, and their dimethyl ethers were accomplished. (R)-(-)-1,3-Butanediol was used as a chiral source of the side chain C6-synthon. The dianion of the benzoic acid moiety was alkylated with C6-bromide to give the desired skeleton. Several β-resorcylic acid derivatives including 1 and 2 were synthesized via hydrogenation, lactonization, demethylation and esterification. The (R)-configuration of the stereogenic center in the side chain was proved by this synthesis. It is confirmed that two phenolic hydroxy groups are required for 1 and 2 to exhibit potato micro-tuber inducing activity.