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• 96517-04-3 (8R,8aS)-5-Isopropyl-3,8-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-2-ol 
• 483-76-1 (+)-δ-cadinene 
• 97182-95-1 (1S,4R)-1-Isopropyl-4,7-dimethyl-5-methylsulfanyl-1,2,3,4-tetrahydro-naphthalene 

Relevant academic research and scientific papers

Sesquiterpene constituents of the liverwort Calypogeia fissa

Four new sesquiterpenes have been identified as constituents of the liverwort Calypogeia fissa: (+)-10β(H)-muurola-3,7(11)-dien-1-ol, (-)-α- alasken-6β-ol, (-)-α-alasken-8-one and 7,8-dehydro-α-acoradiene. (+)- Cadina-1(10),3,7(11)-triene and (+)-cis-cadina-4,6-dien-11-ol were obtained as reaction products from (+)-10β(H)-muurola-3,7(11)-dien-1-ol.

epi-cubebanes from Solidago canadensis

GC-MS of the essential oil prepared by hydrodistillation of the green parts of a specimen of Solidago canadensis collected near Katowice, Poland, revealed two new sesquiterpene hydrocarbons. Their El mass spectra resembled the mass spectrum of β-ylangene (1) but the retention indices of the new compounds differed markedly from this known compound. After isolation of the new compounds by preparative GC their investigation by one- and two-dimensional NMR techniques resulted in the identification of 6-epi-α-cubebene (2) (minor constituent, 1.5%) and 6-epi-β-cubebene (3) (major constituent, 20.5%).

New Cadinene and Bisabolene Derivatives from the Essential Oil of Pulicaria gnaphalodes

From the essential oil of Pulicaria gnaphalodes growing near Tehran some new cadinene derivatives were isolated.The structures of 1,8-oxidocadin-4-enes (6, 7, epimers at C-10), 1(10),4-cadinadien-8α-ol (1), 4,10(14)-cadinadien- and 4, 10(14)-muuroldaien-8-ols (2-5) could be verified by their 1H- and 13C-NMR spectra.Furthermore, the 8α-epimer 9 of the known α-copaen-8β-ol (10), (Z)-γ-curcumen-12-ol (13a) and the esters (Z)-13b-e could be identified.Key Words: Pulicaria gnaphalodes / Compositae / 1,8-Oxidocadin-4-ene / Cadinadien-8-ols / α-Copaen-8-ol / γ-Curcumen-12-ol

ABSOLUTE STEREOCHEMISTRY OF THE CADINENES FROM EUPATORIUM TRAPEZOIDEUM

Chemical examination of Eupatorium trapezoideum has furnished five cadinenes 1a, 2a, 2b, 4a and 5 and a degraded cadinene 3a whose stereostructures are presented in this paper.The absolute stereochemistry of the major component 1a has been determined by application of Horeau's method as well as chemical correlation studies and has been confirmed by X-ray analysis of 1f thus suggesting that it belongs to the amorphane group.

SYNTHESIS OF ARYL METHYLTHIO ETHERS EMPLOYING α-OXOKETENE DITHIOACETALS

Reaction of α-oxoketene dithioacetals with methallyl magnesium chloride followed by acid treatment affords simple and annulated aryl methylthio ethers.The methylthio substituent can be easily removed with Raney Ni, undergo a Ni catalyzed substitution reac