359450-91-2Relevant academic research and scientific papers
In vitro and in silico exploration of IL-2 inhibition by small drug-like molecules
Kalsoom, Saima,Rashid, Umer,Shaukat, Awais,Abdalla, Omer Mohamed,Hussain, Khalida,Khan, Waqasuddin,Nazir, Samina,Mesaik, Mohammad Ahmad,Zaheer-Ul-Haq,Ansari, Farzana Latif
, p. 5739 - 5751 (2013)
Interleukin-2 (IL-2) is an immunoregulatory cytokine produced by T lymphocytes in response to antigen. It is a potent growth and differentiation factor for several cell-types and is structurally related to the four-helix bundle family of cytokines. Here,
Structure based virtual screening-driven identification of monastrol as a potent urease inhibitor
Rashid, Umer,Batool, Iram,Wadood, Abdul,Khan, Ajmal,Ul-Haq, Zaheer,Chaudhary, Muhammad Iqbal,Ansari, Farzana Latif
, p. 47 - 57 (2013/07/27)
Virtual screening uses computer based methods to discover new ligands on the basis of biological structures. Among all virtual screening methods structure based docking has received considerable attention. In an attempt to identify new ligands as urease i
