359454-91-4

Upstream product

• 95452-06-5 tert-butyl(1,3-dithian-2-yl)dimethylsilane 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 243978-61-2 [3R,4S,5R,6R]-4,5-di-O-benzyl-3-O-tert-butyl(dimethyl)silyl-3,4,5,6-tetrahydroxycycloheptan-1-one 1,3-propanedithioketal 
• 243978-65-6 [3R,4S,5S,6R]-4,5-dibenzyloxy-3,6-di-tert-butyl(dimethyl)silyloxycycloheptan-1-one 
• 243978-67-8 [3R,4S,5S,6R]-4,5-dibenzyloxy-3,6-di-tert-butyl(dimethyl)silyloxycycloheptan-1-one 1,3-propanedithioketal 

Downstream Products

• 359454-94-7 N-([3R,4R,5R,6R]-4,5-di-O-benzyl-3,4,5,6-tetrahydroxycycloheptanyl)-N-butylamine 

Relevant academic research and scientific papers

Synthesis and glycosidase inhibitory activity of aminocyclitols with a C6- or a C7-ring

The synthesis of carbasugars and various aminocyclitols, related to voglibose and acarbose used in the treatment of non-insulino-dependant diabetes, is described from C2-symmetrical bis-epoxides derived from D-mannitol. The methodology involves

Efficient access to azadisaccharide analogues

The synthesis of various aminocyclitols as pseudo-azadisaccharide candidates for glycosidase inhibition is described. The strategy involves the reductive amination with several amines of polyhydroxycycloheptanones resulting from a tandem alkylation-cyclis