359454-92-5

Upstream product

• 243978-67-8 [3R,4S,5S,6R]-4,5-dibenzyloxy-3,6-di-tert-butyl(dimethyl)silyloxycycloheptan-1-one 1,3-propanedithioketal 
• 243978-65-6 [3R,4S,5S,6R]-4,5-dibenzyloxy-3,6-di-tert-butyl(dimethyl)silyloxycycloheptan-1-one 
• 157363-85-4 1,2:5,6-Dianhydro-3,4-di-O-benzyl-D-mannitol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 95452-06-5 tert-butyl(1,3-dithian-2-yl)dimethylsilane 

Downstream Products

• 359454-95-8 (1R,2R,3R,4R)-2,3-Bis-benzyloxy-6-(2-hydroxy-1-hydroxymethyl-ethylamino)-cycloheptane-1,4-diol 

Relevant academic research and scientific papers

Synthesis and glycosidase inhibitory activity of aminocyclitols with a C6- or a C7-ring

The synthesis of carbasugars and various aminocyclitols, related to voglibose and acarbose used in the treatment of non-insulino-dependant diabetes, is described from C2-symmetrical bis-epoxides derived from D-mannitol. The methodology involves

Efficient access to azadisaccharide analogues

The synthesis of various aminocyclitols as pseudo-azadisaccharide candidates for glycosidase inhibition is described. The strategy involves the reductive amination with several amines of polyhydroxycycloheptanones resulting from a tandem alkylation-cyclis