35953-53-8Relevant academic research and scientific papers
ON THE STEREOSPECIFIC REDUCTION OF VINYLSULFOXIDES WITH THE POSSIBILITY OF DEUTERIUM LABELING
Theobald, Paula G.,Okamura, William H.
, p. 6565 - 6568 (2007/10/02)
Upon treating triene sulfoxide 2 or 3 in the presence of methanol (internal proton source) in ether with tert-butyllithium, the reduced product 4b or 4c, respectively, is obtaned with retention of configuration.A deuterium label can be incorporated by using methanol-d1 as the internal proton source.
SELECTIVE MIXED COUPLING OF CARBOXYLIC ACIDS (II). -PHOTOLYSIS OF UNSYMMETRICAL DIACYLPEROXIDES WITH ALKENYL-, HALO-, KETO-, CARBOXYL-GROUPS AND A CHIRAL α-CARBON. COMPARISON WITH THE MIXED KOLBE ELECTROLYSIS.
Feldhues, Michael,Schaefer, Hans J.
, p. 4213 - 4236 (2007/10/02)
- Alkenoyl and functionalized alkanoyl dodecanoyl peroxides are prepared in 70 to 97 percent yield and photolyzed at -78 deg C.Thereby 4- to 10-alkenoyl and 4-alkynoyl peroxides afford good yields (56 - 68 percent) of unsymmetrical coupling products.Similarly α- to δ-haloalkanoyl, cholanoyl or 3- and 4-carboxyalkanoyl peroxides can be coupled (40 - 70 percent).The α-chiral diacyl peroxide 1s undergoes the photochemical coupling reaction with 80 percent retention of its configuration.The photolysis of diacyl peroxides at -78 deg C proves to be a favorable supplement of the Kolbe-electrolysis in cases, where the electrolysis fails or produces low yields.
